1. sNCP caused by other non-viral infections (such as trauma), 2. WHO grade III or IV pulmonary hypertension, 3. Malignant tumor in lung and other systems, 4. Lactating women or screening women with positive blood pregnancy test, 5. Idiopathic IgA deficiency, 6. Recent cardiovascular and cerebrovascular events (3 months), 7. Lung transplanted patients, 8. HIV positive patients, 9. According to the researcher's judgment, these subjects will be excluded because of some causes, such as any disease, treatment, or laboratory abnormal history or current evidence, which may confound the results of the study, interfere with the subject's participation in the study procedure, or be not in the best interest of the subject's participation in the study.

1. sNCP caused by other non-viral infections (such as trauma), 2. WHO grade III or IV pulmonary hypertension, 3. Malignant tumor in lung and other systems, 4. Lactating women or screening women with positive blood pregnancy test, 5. Idiopathic IgA deficiency, 6. Recent cardiovascular and cerebrovascular events (3 months), 7. Lung transplanted patients, 8. HIV positive patients, 9. According to the researcher's judgment, these subjects will be excluded because of some causes, such as any disease, treatment, or laboratory abnormal history or current evidence, which may confound the results of the study, interfere with the subject's participation in the study procedure, or be not in the best interest of the subject's participation in the study.