* those who are not pregnant, breastfeeding and pregnant but who do not take effective contraceptive measures; * patients with malignant tumors, other serious systemic diseases and psychosis; * informed consent is not given or does not comply with the test requirements. * co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. * pneumonia caused by bacteria, mycoplasma, chlamydia, legionella, fungi or co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. * obstructive habp / vabp caused by lung cancer or other known causes; long-term history of use of immunosuppressive agents; * history of epilepsy and need for continuous anticonvulsant therapy or anticonvulsant therapy taken within 3 years; * invasive ventilation * shock * other organ failures

* those who are not pregnant, breastfeeding and pregnant but who do not take effective contraceptive measures; * patients with malignant tumors, other serious systemic diseases and psychosis; * informed consent is not given or does not comply with the test requirements. * co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. * pneumonia caused by bacteria, mycoplasma, chlamydia, legionella, fungi or co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. * obstructive habp / vabp caused by lung cancer or other known causes; long-term history of use of immunosuppressive agents; * history of epilepsy and need for continuous anticonvulsant therapy or anticonvulsant therapy taken within 3 years; * invasive ventilation * shock * other organ failures

- those who are not pregnant, breastfeeding and pregnant but who do not take effective contraceptive measures; - patients with malignant tumors, other serious systemic diseases and psychosis; - informed consent is not given or does not comply with the test requirements. - co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. - pneumonia caused by bacteria, mycoplasma, chlamydia, legionella, fungi or co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. - obstructive habp / vabp caused by lung cancer or other known causes; long-term history of use of immunosuppressive agents; - history of epilepsy and need for continuous anticonvulsant therapy or anticonvulsant therapy taken within 3 years; - invasive ventilation - shock - other organ failures

- those who are not pregnant, breastfeeding and pregnant but who do not take effective contraceptive measures; - patients with malignant tumors, other serious systemic diseases and psychosis; - informed consent is not given or does not comply with the test requirements. - co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. - pneumonia caused by bacteria, mycoplasma, chlamydia, legionella, fungi or co-infection of hiv, tuberculosis, influenza virus, adenovirus and other respiratory infection virus. - obstructive habp / vabp caused by lung cancer or other known causes; long-term history of use of immunosuppressive agents; - history of epilepsy and need for continuous anticonvulsant therapy or anticonvulsant therapy taken within 3 years; - invasive ventilation - shock - other organ failures