1. Aged 18 to 75 years old, 2. The diagnosis of new-type coronavirus pneumonia was confirmed by RT-PCR or gene sequencing according to the Diagnosis and Treatment Scheme for Pneumonia of New Coronavirus Infection (Trial Version 6 and Updated) , and the clinical type was general (including severe high-risk factors) and severe, Note: Patients with common new type of coronavirus pneumonia (including severe high-risk factors): patients with common type with multiple lung multiple lesions, or pulmonary imaging shows that the lesion progresses significantly within 50% within 24 to 48 hours, 3. IL-6 is elevated (Roche chemiluminescence detection is recommended), 4. The patient voluntarily signed the informed consent.

1. Aged 18 to 75 years old, 2. The diagnosis of new-type coronavirus pneumonia was confirmed by RT-PCR or gene sequencing according to the Diagnosis and Treatment Scheme for Pneumonia of New Coronavirus Infection (Trial Version 6 and Updated) , and the clinical type was general (including severe high-risk factors) and severe, Note: Patients with common new type of coronavirus pneumonia (including severe high-risk factors): patients with common type with multiple lung multiple lesions, or pulmonary imaging shows that the lesion progresses significantly within 50% within 24 to 48 hours, 3. IL-6 is elevated (Roche chemiluminescence detection is recommended), 4. The patient voluntarily signed the informed consent.