1. Critical new pneumonia infection that meets one of the following conditions: respiratory failure occurs and requires mechanical ventilation, shock, combined organ failure requires ICU monitoring and treatment 2. Known allergies to Ixekizumab or antiviral drugs, 3. ALT / AST> 5 times ULN, neutrophils <0.5x10^9/L, Platelets less than 50x10^9/L, 4. Patients with impaired renal function: serum creatinine >=2 mg/dl (176 umol/l), 5. Combined with severe underlying diseases, the expected life cycle is less than 3 months, 6. Active hepatitis, patients with definite severe bacterial and fungal infections, tuberculosis infection, and HIV infection, 7. Clear diagnosis of malignant tumors such as lymphoproliferative diseases, 8. Known active Crohn's disease, 9. Pregnant or lactating women, 10. Participated in other interventional clinical trials in the past 3 months, 11. Other conditions that the researcher considers unsuitable.

1. Critical new pneumonia infection that meets one of the following conditions: respiratory failure occurs and requires mechanical ventilation, shock, combined organ failure requires ICU monitoring and treatment 2. Known allergies to Ixekizumab or antiviral drugs, 3. ALT / AST> 5 times ULN, neutrophils <0.5x10^9/L, Platelets less than 50x10^9/L, 4. Patients with impaired renal function: serum creatinine >=2 mg/dl (176 umol/l), 5. Combined with severe underlying diseases, the expected life cycle is less than 3 months, 6. Active hepatitis, patients with definite severe bacterial and fungal infections, tuberculosis infection, and HIV infection, 7. Clear diagnosis of malignant tumors such as lymphoproliferative diseases, 8. Known active Crohn's disease, 9. Pregnant or lactating women, 10. Participated in other interventional clinical trials in the past 3 months, 11. Other conditions that the researcher considers unsuitable.