inclusion criteria: patients included in the study must meet all the following criteria: * patient or legally authorized representative able to provide informed consent * presence of sars-cov-2 infection documented by positive rt-pcr testing or history of positive rt-pcr test for sars-cov-2 within 7 days of screening * radiologic findings compatible with diagnosis of sars-cov-2 pulmonary infection * hypoxemia as defined by any of the following: * spo2 ≤94% on room air, or * requirement for ≥2l/m o2 per standard nasal cannula to maintain spo2≥94%, but not requiring high-flow nasal cannula (defined as ≥30 l/m), and * negative pregnancy test for women of childbearing potential and, must be willing to use birth control for the duration of the study.

inclusion criteria: patients included in the study must meet all the following criteria: * patient or legally authorized representative able to provide informed consent * presence of sars-cov-2 infection documented by positive rt-pcr testing or history of positive rt-pcr test for sars-cov-2 within 7 days of screening * radiologic findings compatible with diagnosis of sars-cov-2 pulmonary infection * hypoxemia as defined by any of the following: * spo2 ≤94% on room air, or * requirement for ≥2l/m o2 per standard nasal cannula to maintain spo2≥94%, but not requiring high-flow nasal cannula (defined as ≥30 l/m), and * negative pregnancy test for women of childbearing potential and, must be willing to use birth control for the duration of the study.

inclusion criteria: patients included in the study must meet all the following criteria: - patient or legally authorized representative able to provide informed consent - presence of sars-cov-2 infection documented by positive rt-pcr testing or history of positive rt-pcr test for sars-cov-2 within 7 days of screening - radiologic findings compatible with diagnosis of sars-cov-2 pulmonary infection - hypoxemia as defined by any of the following: - spo2 ≤94% on room air, or - requirement for ≥2l/m o2 per standard nasal cannula to maintain spo2≥94%, but not requiring high-flow nasal cannula (defined as ≥30 l/m), and - negative pregnancy test for women of childbearing potential and, must be willing to use birth control for the duration of the study.

inclusion criteria: patients included in the study must meet all the following criteria: - patient or legally authorized representative able to provide informed consent - presence of sars-cov-2 infection documented by positive rt-pcr testing or history of positive rt-pcr test for sars-cov-2 within 7 days of screening - radiologic findings compatible with diagnosis of sars-cov-2 pulmonary infection - hypoxemia as defined by any of the following: - spo2 ≤94% on room air, or - requirement for ≥2l/m o2 per standard nasal cannula to maintain spo2≥94%, but not requiring high-flow nasal cannula (defined as ≥30 l/m), and - negative pregnancy test for women of childbearing potential and, must be willing to use birth control for the duration of the study.

inclusion criteria: 1. signed informed consent form and able to give informed consent 2. age 18-75 years 3. presence of sars-cov-2 infection documented by positive rt-pcr testing or history of positive rt-pcr test for sars-cov-2 within 7 days 4. radiologic findings compatible with diagnosis of sars-cov-2 pulmonary infection with no alternative explanation for the radiologic findings 5. hypoxemia as defined by any of the following: 1. spo2 ≤94% on room air, or 2. requirement for ≥2l/m o2 per standard nasal cannula, but not requiring high-flow nasal cannula (defined as ≥30 l/m) 6. women of childbearing potential must have a negative pregnancy test

inclusion criteria: 1. signed informed consent form and able to give informed consent 2. age 18-75 years 3. presence of sars-cov-2 infection documented by positive rt-pcr testing or history of positive rt-pcr test for sars-cov-2 within 7 days 4. radiologic findings compatible with diagnosis of sars-cov-2 pulmonary infection with no alternative explanation for the radiologic findings 5. hypoxemia as defined by any of the following: 1. spo2 ≤94% on room air, or 2. requirement for ≥2l/m o2 per standard nasal cannula, but not requiring high-flow nasal cannula (defined as ≥30 l/m) 6. women of childbearing potential must have a negative pregnancy test