(1) novel coronavirus pneumonia is a disease or condition beyond the pneumonia. That is, according to the researchers' judgement, the subjects will be at risk for taking part in the research, or will have an impact on the results of the study and the ability of the subjects to participate in the study, (2) A woman who is pregnant or breastfeeding or who plans to be pregnant during the study period, (3) Combined with heart, liver, kidney, hematopoietic system and other important organs or systems of serious primary diseases, (4) Severe and critical patients: respiratory distress, RR >=30 times / min, in resting state, oxygen saturation <= 93%, arterial partial pressure of oxygen (PaO2) / concentration of oxygen (FiO2) < 300MMHG, respiratory failure, mechanical ventilation, shock, other organ failure requiring ICU monitoring and treatment, (5) Patients over 70 years old, (6) Patients with mental disorders and cognitive disorders, (7) Those who have poor compliance, are unwilling to participate in the project or do not sign the informed consent during their stay in the hospital. There are doubts about the validity of informed consent: subjects with mental illness, mental retardation, poor motivation, drug abuse (including drugs and alcohol) or other disease history restricting the validity of informed consent in this study, (8) Patients with glucocorticoid, (9) The researchers think it is not suitable to participate in this study.

(1) novel coronavirus pneumonia is a disease or condition beyond the pneumonia. That is, according to the researchers' judgement, the subjects will be at risk for taking part in the research, or will have an impact on the results of the study and the ability of the subjects to participate in the study, (2) A woman who is pregnant or breastfeeding or who plans to be pregnant during the study period, (3) Combined with heart, liver, kidney, hematopoietic system and other important organs or systems of serious primary diseases, (4) Severe and critical patients: respiratory distress, RR >=30 times / min, in resting state, oxygen saturation <= 93%, arterial partial pressure of oxygen (PaO2) / concentration of oxygen (FiO2) < 300MMHG, respiratory failure, mechanical ventilation, shock, other organ failure requiring ICU monitoring and treatment, (5) Patients over 70 years old, (6) Patients with mental disorders and cognitive disorders, (7) Those who have poor compliance, are unwilling to participate in the project or do not sign the informed consent during their stay in the hospital. There are doubts about the validity of informed consent: subjects with mental illness, mental retardation, poor motivation, drug abuse (including drugs and alcohol) or other disease history restricting the validity of informed consent in this study, (8) Patients with glucocorticoid, (9) The researchers think it is not suitable to participate in this study.