Subjects who meet the following conditions can become subjects of this study: 1. Will sign written informed consent. Adolescents or patients who cannot sign informed consent must obtain informed consent from the guardian, 2. Chinese aged >=18 years, 3. In accordance with NCP criteria for severe and critical illness, namely Pneumonitis Diagnosis and Treatment Scheme for Novel Coronavirus Infection (Trial Version 6) . Combined with the following epidemiological history, clinical manifestations, and pathogenic examinations to make a comprehensive judgment. 4. The course of disease is within 14 days after the onset of illness, 5. Will take nasopharyngeal or oropharyngeal swabs before administration.

Subjects who meet the following conditions can become subjects of this study: 1. Will sign written informed consent. Adolescents or patients who cannot sign informed consent must obtain informed consent from the guardian, 2. Chinese aged >=18 years, 3. In accordance with NCP criteria for severe and critical illness, namely Pneumonitis Diagnosis and Treatment Scheme for Novel Coronavirus Infection (Trial Version 6) . Combined with the following epidemiological history, clinical manifestations, and pathogenic examinations to make a comprehensive judgment. 4. The course of disease is within 14 days after the onset of illness, 5. Will take nasopharyngeal or oropharyngeal swabs before administration.