(1) RT-PCR detection of the respiratory or blood samples shows positive nucleic acid of the novel coronavirus, (2) Gene sequence of the virus in respiratory or blood samples are highly homologous to the known coronaviruses, (3) The CT images of chest shows radiographic features of pneumonia, (4) Patients with severe or critical conditions, (5) Aged >=18, male or female, (6) The subjects should volunteer to join the study, sign the informed consent, have good compliance and cooperate with the follow-up.

(1) RT-PCR detection of the respiratory or blood samples shows positive nucleic acid of the novel coronavirus, (2) Gene sequence of the virus in respiratory or blood samples are highly homologous to the known coronaviruses, (3) The CT images of chest shows radiographic features of pneumonia, (4) Patients with severe or critical conditions, (5) Aged >=18, male or female, (6) The subjects should volunteer to join the study, sign the informed consent, have good compliance and cooperate with the follow-up.