1. critically ill patients based on the New Protocol for Diagnosis and Treatment of NCP, 2. Patients with eye diseases (such as cataract, conjunctivitis, glaucoma) 3. Severe liver disease (such as AST > 3 ULN), 4. Patients with severe renal insufficiency (estimated glomerular filtration rate <=30ml/min/1.73m2) or continuous renal replacement therapy, hemodialysis or peritoneal dialysis, 5. Pregnant or breast-feeding women, 6. Patients may be transferred to non-designated hospitals within 72 hours, 7. Patients who have participated in other clinical trials in the past 7 days, 8. Allergic constitution, such as those who are allergic to two or over twodrugs ,with history of food allergies, or known to be allergic to the ingredients of this drug, 9. In the opinion of the investigator, subjects who are not suitable for enrollment or with any factors that affect the outcome of the trial.

1. critically ill patients based on the New Protocol for Diagnosis and Treatment of NCP, 2. Patients with eye diseases (such as cataract, conjunctivitis, glaucoma) 3. Severe liver disease (such as AST > 3 ULN), 4. Patients with severe renal insufficiency (estimated glomerular filtration rate <=30ml/min/1.73m2) or continuous renal replacement therapy, hemodialysis or peritoneal dialysis, 5. Pregnant or breast-feeding women, 6. Patients may be transferred to non-designated hospitals within 72 hours, 7. Patients who have participated in other clinical trials in the past 7 days, 8. Allergic constitution, such as those who are allergic to two or over twodrugs ,with history of food allergies, or known to be allergic to the ingredients of this drug, 9. In the opinion of the investigator, subjects who are not suitable for enrollment or with any factors that affect the outcome of the trial.