1. The serious NCP patients who can neither swallow medicines nor take medicine via stomach tube, and the critical serious NCP patients, 2. Those with severe hypo-immunity due to, but not limited to, one of the following reasons: 1) HIV/AIDS, the condition is still unstable in the process of mediation and /or the last detection value of CD4 plus T lymphocyte is less than 200, 2) Those who received organ transplantation and are given systematic immune treatment, 3) Long-term systematic administration of corticosteroids is defined as daily intake of over 40 mg of Prednisone or equivalent in 14 days before the first medication, 4. Patients who are unable to take medicines orally or via stomach tube, 5. Patients who are allergic to the test medicines, 6. Those with poor communication skills, understanding, cooperation or compliance and those cannot follow protocol to complete the study, 7. Those suffered with serious diseases such as malignancy, mental diseases and so on, or those ineligible to participate the study according to investigators judgement.

1. The serious NCP patients who can neither swallow medicines nor take medicine via stomach tube, and the critical serious NCP patients, 2. Those with severe hypo-immunity due to, but not limited to, one of the following reasons: 1) HIV/AIDS, the condition is still unstable in the process of mediation and /or the last detection value of CD4 plus T lymphocyte is less than 200, 2) Those who received organ transplantation and are given systematic immune treatment, 3) Long-term systematic administration of corticosteroids is defined as daily intake of over 40 mg of Prednisone or equivalent in 14 days before the first medication, 4. Patients who are unable to take medicines orally or via stomach tube, 5. Patients who are allergic to the test medicines, 6. Those with poor communication skills, understanding, cooperation or compliance and those cannot follow protocol to complete the study, 7. Those suffered with serious diseases such as malignancy, mental diseases and so on, or those ineligible to participate the study according to investigators judgement.