1. Critical type: If one of the following conditions is met (1) Respiratory failure occurs and mechanical ventilation is needed, (2) Shock occurred, (3) Patients with other organ failure need ICU monitoring treatment, 2. Severe type: If one of the following conditions is met (1) Respiratory distress, RR >= 30 beats / min, (2) In resting state, finger oxygen saturation (SaO2) <= 93%, (3) Partial pressure of arterial oxygen (PaO2) / concentration of oxygen inhaled (FiO2)<= 300mmHg, 3. Those who have a history of allergy to this class of drugs and / or severe allergic constitution, 4. The results of laboratory tests are abnormal: (1) Hematological dysfunction is defined as: 1) Platelet (PLT) count <100x10^9/L, 2) Hemoglobin (Hb) level <90g/L, (2) Abnormal liver function is defined as: 1) Level of total bilirubin(TBil) >2 ULN, 2) The levels of aspartate aminotransferase (AST) and Alanine transaminase (ALT)>3 ULN, 3) Definition of renal dysfunction: Serum creatinine>1.5 ULN, or calculated creatinine clearance<50ml/min, 4) Definition of abnormal blood coagulation: International normalized ratio(INR) >1.5 ULN, and the prothrombin time ((PT)) or activated partial thromboplastin time (aPTT) 1.5 ULN, unless the subject is receiving anticoagulant therapy, 5. Abidor was used before inclusion(Tablets, capsules, granules), 6. Women who are nursing or pregnant, 7. Serum or urine pregnancy tests were positive for women of child-bearing age, 8. Immunodeficient patient(Patients with malignant tumors, Organ or bone marrow transplant, HIV patient, those who took immunosuppressive drugs within 3 months before the screening test ), 9. With the following history of present illness: (1) Neurological and neurodevelopmental disorders, These include diseases of the brain, spinal cord, peripheral nerves and muscles(Such as cerebral palsy, epilepsy, stroke, mental retardation, moderate to severe developmental delay, muscular malnutrition or spinal cord injury ), (2) Circulation system disease( congenital heart disease, Congestive heart failure or coronary artery disease), (3) Severe heart disease or a history of clinically significant arrhythmias that the researchers believe will affect participants' safety (According to the ECG or medical history), 10. Other patients considered ineligible for this study were considered ineligible by the investigators.

1. Critical type: If one of the following conditions is met (1) Respiratory failure occurs and mechanical ventilation is needed, (2) Shock occurred, (3) Patients with other organ failure need ICU monitoring treatment, 2. Severe type: If one of the following conditions is met (1) Respiratory distress, RR >= 30 beats / min, (2) In resting state, finger oxygen saturation (SaO2) <= 93%, (3) Partial pressure of arterial oxygen (PaO2) / concentration of oxygen inhaled (FiO2)<= 300mmHg, 3. Those who have a history of allergy to this class of drugs and / or severe allergic constitution, 4. The results of laboratory tests are abnormal: (1) Hematological dysfunction is defined as: 1) Platelet (PLT) count <100x10^9/L, 2) Hemoglobin (Hb) level <90g/L, (2) Abnormal liver function is defined as: 1) Level of total bilirubin(TBil) >2 ULN, 2) The levels of aspartate aminotransferase (AST) and Alanine transaminase (ALT)>3 ULN, 3) Definition of renal dysfunction: Serum creatinine>1.5 ULN, or calculated creatinine clearance<50ml/min, 4) Definition of abnormal blood coagulation: International normalized ratio(INR) >1.5 ULN, and the prothrombin time ((PT)) or activated partial thromboplastin time (aPTT) 1.5 ULN, unless the subject is receiving anticoagulant therapy, 5. Abidor was used before inclusion(Tablets, capsules, granules), 6. Women who are nursing or pregnant, 7. Serum or urine pregnancy tests were positive for women of child-bearing age, 8. Immunodeficient patient(Patients with malignant tumors, Organ or bone marrow transplant, HIV patient, those who took immunosuppressive drugs within 3 months before the screening test ), 9. With the following history of present illness: (1) Neurological and neurodevelopmental disorders, These include diseases of the brain, spinal cord, peripheral nerves and muscles(Such as cerebral palsy, epilepsy, stroke, mental retardation, moderate to severe developmental delay, muscular malnutrition or spinal cord injury ), (2) Circulation system disease( congenital heart disease, Congestive heart failure or coronary artery disease), (3) Severe heart disease or a history of clinically significant arrhythmias that the researchers believe will affect participants' safety (According to the ECG or medical history), 10. Other patients considered ineligible for this study were considered ineligible by the investigators.