1. Pregnant or lactating women, 2. There are comorbidities that affect the judgment of the efficacy, such as those with malignant tumors or long-term immunosuppressants, 3. The investigator believes that the patient has other conditions that are not suitable for enrollment, 4. Allergic to dimethyl sulfoxide (DMSO), dextran 40 or human albumin, 5. Contraindicated signs of artificial liver therapy

1. Pregnant or lactating women, 2. There are comorbidities that affect the judgment of the efficacy, such as those with malignant tumors or long-term immunosuppressants, 3. The investigator believes that the patient has other conditions that are not suitable for enrollment, 4. Allergic to dimethyl sulfoxide (DMSO), dextran 40 or human albumin, 5. Contraindicated signs of artificial liver therapy