1. Patients with severe 2019-nCoV pneumonia met one of the following conditions: respiratory distress, RR >= 30 times / min, or SaO2 / SpO2 <= 93% in resting state, or arterial partial pressure of oxygen (PaO2) / concentration of oxygen (FiO2) <= 300MMHG (1mmhg = 0.133kpa), 2. Patients with critical 2019-nCoV pneumonia met one of the following conditions: respiratory failure and mechanical ventilation required, or shock, or combined with other organ failure required ICU monitoring treatment, 3. Severe liver disease (such as child Pugh score >= C, AST > 5 times upper limit), 4. Patients were allergic to the components of ASC09 / ritonavir compound tablets, 5. Patients with definite contraindications in the label of ritonavir tablets, 6. Female subjects pregnancy test was positive during the screening period, 7. Patients who are taking HIV protease inhibitor drugs, 8. Physician judged the patient was not suitable for this clinical trial (for example, patient may be transferred to another hospital during the study period, patient with multiple basic diseases, etc.).

1. Patients with severe 2019-nCoV pneumonia met one of the following conditions: respiratory distress, RR >= 30 times / min, or SaO2 / SpO2 <= 93% in resting state, or arterial partial pressure of oxygen (PaO2) / concentration of oxygen (FiO2) <= 300MMHG (1mmhg = 0.133kpa), 2. Patients with critical 2019-nCoV pneumonia met one of the following conditions: respiratory failure and mechanical ventilation required, or shock, or combined with other organ failure required ICU monitoring treatment, 3. Severe liver disease (such as child Pugh score >= C, AST > 5 times upper limit), 4. Patients were allergic to the components of ASC09 / ritonavir compound tablets, 5. Patients with definite contraindications in the label of ritonavir tablets, 6. Female subjects pregnancy test was positive during the screening period, 7. Patients who are taking HIV protease inhibitor drugs, 8. Physician judged the patient was not suitable for this clinical trial (for example, patient may be transferred to another hospital during the study period, patient with multiple basic diseases, etc.).