1. Have any known disease that seriously affects the immune system, such as a history of infection with the human immunodeficiency virus (HIV), or malignant tumors of the blood system or solid organs, or splenectomy, 2. Other circumstances that the researcher considers inappropriate to participate in this study.

1. Have any known disease that seriously affects the immune system, such as a history of infection with the human immunodeficiency virus (HIV), or malignant tumors of the blood system or solid organs, or splenectomy, 2. Other circumstances that the researcher considers inappropriate to participate in this study.