1) Any situation that makes the programme cannot proceed safely, 2) patients who have used Kaletra or remdesivir, 3) no clinical or chest imaging manifestations, 4) In the state of no oxygen at rest, the patient's SPO2 <= 94% or the oxygenation index is less than 300mmHg respiratory rate >= 24/min, 5) Patients who need to be admitted to ICU judged by clinicians, 6) Known allergy or hypersensitivity reaction to lopinavir / ritonavir, 7) Increase in alanine aminotransferase (ALT) / aspartate aminotransferase (AST) is more than 3 times the upper limit of normal, 8) Drugs that are forbidden to be treated with lopinavir / ritonavir and cannot be replaced or stopped during the study period, such as afzosin, amiodarone, fusidic acid, astemizole, terfenadine, piperazine, dihydroergomethane, ergometrine Alkali, ergotamine, methylergometrine, cisapride, lovastatin, simvastatin, sildenafil, vartanafi, midazolam, triazolam, St. John's wort (Hypericum perforatum extract), etc., 9) Pregnancy: positive pregnancy test for women of childbearing age, 10) lactating women did not stop lactation, 11) Known HIV infection, because of concerns about the development of resistance to lopinavir/rionavir if used without combination with other anti-HIV drugs, 12) Patient likely to be transferred to a non-participating hospital within 72 hours.

1) Any situation that makes the programme cannot proceed safely, 2) patients who have used Kaletra or remdesivir, 3) no clinical or chest imaging manifestations, 4) In the state of no oxygen at rest, the patient's SPO2 <= 94% or the oxygenation index is less than 300mmHg respiratory rate >= 24/min, 5) Patients who need to be admitted to ICU judged by clinicians, 6) Known allergy or hypersensitivity reaction to lopinavir / ritonavir, 7) Increase in alanine aminotransferase (ALT) / aspartate aminotransferase (AST) is more than 3 times the upper limit of normal, 8) Drugs that are forbidden to be treated with lopinavir / ritonavir and cannot be replaced or stopped during the study period, such as afzosin, amiodarone, fusidic acid, astemizole, terfenadine, piperazine, dihydroergomethane, ergometrine Alkali, ergotamine, methylergometrine, cisapride, lovastatin, simvastatin, sildenafil, vartanafi, midazolam, triazolam, St. John's wort (Hypericum perforatum extract), etc., 9) Pregnancy: positive pregnancy test for women of childbearing age, 10) lactating women did not stop lactation, 11) Known HIV infection, because of concerns about the development of resistance to lopinavir/rionavir if used without combination with other anti-HIV drugs, 12) Patient likely to be transferred to a non-participating hospital within 72 hours.