[{"arm_notes": "", "treatment_id": null, "treatment_name": "This is a multisite; 3 stage inpatient study of the Angiotensin II Receptor Blocker Losartan for treatment of COVID-19. The three stages will be recruited sequentially. In the first stage; 9 participants will be allocated to the active treatment. The first intervention studied will be Losartan 25mg tablet once daily; for 7 days; or their entire admission (whichever is longer).Following complete recruitment to the first stage; participants will be allocated to the second stage of the study. In the second stage; 9 participants will start at 25mg Losartan. If hemodynamically stable after 24 hours; they will increase dose to 25mg twice daily for 7 days; or their entire admission (whichever is longer).If not (clinical decision) the participant will stay on 25mg daily for 7 days; or the remainder of for their admission (whichever is longer).Following complete recruitment to the first and second stages; participants will be allocated to the third stage of the study. In the third stage; 9 participants will start on 25 mg Losartan daily. If hemodynamically stable after 24 hours; they will increase dose to 25mg twice daily. Then; if hemodynamically stable after further 24 hours; they will increase dose again to 25mg morning and 50mg night. After a further 24 hours; and if the participant is hemodynamically stable; they will increase dose to 50mg twice daily for 7 days; or the remainder of for their admission (whichever is longer).For all stages; the dose will be held if the blood pressure systolic reading is less than 100mmHg; and/or a renal function decrease of greater than 30% from baseline is observed; or serum potassium greater than permitted by the institutional upper limit of normal (ULN) occurs. Losartan will be restarted at the", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 744, "treatment_name": "Losartan", "treatment_type": "Cardiovascular agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]