1. subjects with anemia (male: \<12 g/dl, females: \<11 g/dl) 2. subjects with more than 2.5 times upper limit of alt \& ast parameters. 3. subjects not willing to stop intake of any vitamin/s or mineral/s supplements during the trial except for those allowed in the study. 4. subjects with acute symptomatic covid-19 infection indicated by fever, dry cough and severe respiratory distress. 5. subjects with spo2 \< 90%. 6. subjects with history of genetic disorders. 7. subjects with history of: 1. anaphylactic or allergic reaction to a previous dose of covid-19 vaccine 2. immediate or delayed-onset anaphylaxis or allergic reaction to vaccines or injectable therapies, pharmaceutical products, food-items etc. 8. pregnancy \& lactation: a. pregnant \& lactating women have not been part of any covid-19 vaccine clinical trial so far. therefore, women who are pregnant or not sure of their pregnancy; and lactating women should not receive covid-19 vaccine at this time 9. provisional / temporary contraindications: 1. persons having active symptoms of sars-cov-2 infection. 2. sars-cov-2 patients who have been given anti-sars-cov-2 monoclonal antibodies or convalescent plasma 3. signs of acute infection or illness 4. hospitalized patients due to any illness. 10. subjects with known history (diagnosed case) of porphyria, or chronic serious liver disease, kidney disease or heart problems. 11. subjects with frequent complaints of cold, fever, cough. 12. subjects with irritable bowel syndrome. 13. subjects who are frequent travelers or are planning to travel. 14. subject has demonstrated previous intolerance of 5-ala and/or sfc by topical or oral administration. 15. subjects with known allergy to 5-ala containing foods (spinach, shitake mushroom, octopus, baker's yeast, wine, vinegar, sake less). 16. subjects on vitamin d supplements 17. males and females of reproductive potential who have not agreed to use an adequate method of contraception during the study 1. for females, adequate birth control methods will be defined as: hormonal contraceptives, intrauterine device or double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. 2. for males, adequate birth control methods will be defined as double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. 3. for females, menopause is defined as one year without menses; if in question, a follicle-stimulating hormone of \>40 u/ml must be documented. hysterectomy, bilateral oophorectomy, or bilateral tubal ligation must be documented, as applicable. 18. subjects who are unable or unwilling to comply with requirements of the clinical trial. 19. participation in any other clinical trial of an experimental treatment for covid-19. 20. subjects having any other family member participating in this study. 21. subjects who may be excluded at the investigator's discretion.

1. subjects with anemia (male: \<12 g/dl, females: \<11 g/dl) 2. subjects with more than 2.5 times upper limit of alt \& ast parameters. 3. subjects not willing to stop intake of any vitamin/s or mineral/s supplements during the trial except for those allowed in the study. 4. subjects with acute symptomatic covid-19 infection indicated by fever, dry cough and severe respiratory distress. 5. subjects with spo2 \< 90%. 6. subjects with history of genetic disorders. 7. subjects with history of: 1. anaphylactic or allergic reaction to a previous dose of covid-19 vaccine 2. immediate or delayed-onset anaphylaxis or allergic reaction to vaccines or injectable therapies, pharmaceutical products, food-items etc. 8. pregnancy \& lactation: a. pregnant \& lactating women have not been part of any covid-19 vaccine clinical trial so far. therefore, women who are pregnant or not sure of their pregnancy; and lactating women should not receive covid-19 vaccine at this time 9. provisional / temporary contraindications: 1. persons having active symptoms of sars-cov-2 infection. 2. sars-cov-2 patients who have been given anti-sars-cov-2 monoclonal antibodies or convalescent plasma 3. signs of acute infection or illness 4. hospitalized patients due to any illness. 10. subjects with known history (diagnosed case) of porphyria, or chronic serious liver disease, kidney disease or heart problems. 11. subjects with frequent complaints of cold, fever, cough. 12. subjects with irritable bowel syndrome. 13. subjects who are frequent travelers or are planning to travel. 14. subject has demonstrated previous intolerance of 5-ala and/or sfc by topical or oral administration. 15. subjects with known allergy to 5-ala containing foods (spinach, shitake mushroom, octopus, baker's yeast, wine, vinegar, sake less). 16. subjects on vitamin d supplements 17. males and females of reproductive potential who have not agreed to use an adequate method of contraception during the study 1. for females, adequate birth control methods will be defined as: hormonal contraceptives, intrauterine device or double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. 2. for males, adequate birth control methods will be defined as double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. 3. for females, menopause is defined as one year without menses; if in question, a follicle-stimulating hormone of \>40 u/ml must be documented. hysterectomy, bilateral oophorectomy, or bilateral tubal ligation must be documented, as applicable. 18. subjects who are unable or unwilling to comply with requirements of the clinical trial. 19. participation in any other clinical trial of an experimental treatment for covid-19. 20. subjects having any other family member participating in this study. 21. subjects who may be excluded at the investigator's discretion.

subjects with anemia (male: <12 g/dl, females: <11 g/dl) subjects with more than 2.5 times upper limit of alt & ast parameters. subjects not willing to stop intake of any vitamin/s or mineral/s supplements during the trial except for those allowed in the study. subjects with acute symptomatic covid-19 infection indicated by fever, dry cough and severe respiratory distress. subjects with spo2 < 90%. subjects with history of genetic disorders. subjects with history of: anaphylactic or allergic reaction to a previous dose of covid-19 vaccine immediate or delayed-onset anaphylaxis or allergic reaction to vaccines or injectable therapies, pharmaceutical products, food-items etc. pregnancy & lactation: a. pregnant & lactating women have not been part of any covid-19 vaccine clinical trial so far. therefore, women who are pregnant or not sure of their pregnancy; and lactating women should not receive covid-19 vaccine at this time provisional / temporary contraindications: persons having active symptoms of sars-cov-2 infection. sars-cov-2 patients who have been given anti-sars-cov-2 monoclonal antibodies or convalescent plasma signs of acute infection or illness hospitalized patients due to any illness. subjects with known history (diagnosed case) of porphyria, or chronic serious liver disease, kidney disease or heart problems. subjects with frequent complaints of cold, fever, cough. subjects with irritable bowel syndrome. subjects who are frequent travelers or are planning to travel. subject has demonstrated previous intolerance of 5-ala and/or sfc by topical or oral administration. subjects with known allergy to 5-ala containing foods (spinach, shitake mushroom, octopus, baker's yeast, wine, vinegar, sake less). subjects on vitamin d supplements males and females of reproductive potential who have not agreed to use an adequate method of contraception during the study for females, adequate birth control methods will be defined as: hormonal contraceptives, intrauterine device or double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. for males, adequate birth control methods will be defined as double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. for females, menopause is defined as one year without menses; if in question, a follicle-stimulating hormone of >40 u/ml must be documented. hysterectomy, bilateral oophorectomy, or bilateral tubal ligation must be documented, as applicable. subjects who are unable or unwilling to comply with requirements of the clinical trial. participation in any other clinical trial of an experimental treatment for covid-19. subjects having any other family member participating in this study. subjects who may be excluded at the investigator's discretion.

subjects with anemia (male: <12 g/dl, females: <11 g/dl) subjects with more than 2.5 times upper limit of alt & ast parameters. subjects not willing to stop intake of any vitamin/s or mineral/s supplements during the trial except for those allowed in the study. subjects with acute symptomatic covid-19 infection indicated by fever, dry cough and severe respiratory distress. subjects with spo2 < 90%. subjects with history of genetic disorders. subjects with history of: anaphylactic or allergic reaction to a previous dose of covid-19 vaccine immediate or delayed-onset anaphylaxis or allergic reaction to vaccines or injectable therapies, pharmaceutical products, food-items etc. pregnancy & lactation: a. pregnant & lactating women have not been part of any covid-19 vaccine clinical trial so far. therefore, women who are pregnant or not sure of their pregnancy; and lactating women should not receive covid-19 vaccine at this time provisional / temporary contraindications: persons having active symptoms of sars-cov-2 infection. sars-cov-2 patients who have been given anti-sars-cov-2 monoclonal antibodies or convalescent plasma signs of acute infection or illness hospitalized patients due to any illness. subjects with known history (diagnosed case) of porphyria, or chronic serious liver disease, kidney disease or heart problems. subjects with frequent complaints of cold, fever, cough. subjects with irritable bowel syndrome. subjects who are frequent travelers or are planning to travel. subject has demonstrated previous intolerance of 5-ala and/or sfc by topical or oral administration. subjects with known allergy to 5-ala containing foods (spinach, shitake mushroom, octopus, baker's yeast, wine, vinegar, sake less). subjects on vitamin d supplements males and females of reproductive potential who have not agreed to use an adequate method of contraception during the study for females, adequate birth control methods will be defined as: hormonal contraceptives, intrauterine device or double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. for males, adequate birth control methods will be defined as double barrier contraception, i.e., condom + diaphragm, condom or diaphragm + spermicidal gel or foam. for females, menopause is defined as one year without menses; if in question, a follicle-stimulating hormone of >40 u/ml must be documented. hysterectomy, bilateral oophorectomy, or bilateral tubal ligation must be documented, as applicable. subjects who are unable or unwilling to comply with requirements of the clinical trial. participation in any other clinical trial of an experimental treatment for covid-19. subjects having any other family member participating in this study. subjects who may be excluded at the investigator's discretion.