inclusion criteria: * age ≥ 18 years at time of signing the informed consent form (icf). * sars-cov-2 infection documented by rt-pcr within 7 days prior to randomization. * hospitalized patients who meet the criteria of moderate or severe covid-19. * patients who are not pregnant, based on urine pregnancy test during screening, and randomization. * female patients of childbearing potential practice effective contraception during the study and be willing and able to continue contraception for 60 days after their dose of study treatment. * male patient and/or female patient's partner agree to use condoms or should have undergone vasectomy or spermicide in addition to female contraception for additional protection against conception for 60 days after their dose of study treatment. * patients who are anticipated to available for the entire study period and is capable of understanding and communicating with the investigators and clinical study facility staff. * patients who agree to give written informed consent and are willing to participate in the study.

inclusion criteria: * age ≥ 18 years at time of signing the informed consent form (icf). * sars-cov-2 infection documented by rt-pcr within 7 days prior to randomization. * hospitalized patients who meet the criteria of moderate or severe covid-19. * patients who are not pregnant, based on urine pregnancy test during screening, and randomization. * female patients of childbearing potential practice effective contraception during the study and be willing and able to continue contraception for 60 days after their dose of study treatment. * male patient and/or female patient's partner agree to use condoms or should have undergone vasectomy or spermicide in addition to female contraception for additional protection against conception for 60 days after their dose of study treatment. * patients who are anticipated to available for the entire study period and is capable of understanding and communicating with the investigators and clinical study facility staff. * patients who agree to give written informed consent and are willing to participate in the study.

inclusion criteria: age ≥ 18 years at time of signing the informed consent form (icf). sars-cov-2 infection documented by rt-pcr within 7 days prior to randomization. hospitalized patients who meet the criteria of moderate or severe covid-19. patients who are not pregnant, based on urine pregnancy test during screening, and randomization. female patients of childbearing potential practice effective contraception during the study and be willing and able to continue contraception for 60 days after their dose of study treatment. male patient and/or female patient's partner agree to use condoms or should have undergone vasectomy or spermicide in addition to female contraception for additional protection against conception for 60 days after their dose of study treatment. patients who are anticipated to available for the entire study period and is capable of understanding and communicating with the investigators and clinical study facility staff. patients who agree to give written informed consent and are willing to participate in the study.

inclusion criteria: age ≥ 18 years at time of signing the informed consent form (icf). sars-cov-2 infection documented by rt-pcr within 7 days prior to randomization. hospitalized patients who meet the criteria of moderate or severe covid-19. patients who are not pregnant, based on urine pregnancy test during screening, and randomization. female patients of childbearing potential practice effective contraception during the study and be willing and able to continue contraception for 60 days after their dose of study treatment. male patient and/or female patient's partner agree to use condoms or should have undergone vasectomy or spermicide in addition to female contraception for additional protection against conception for 60 days after their dose of study treatment. patients who are anticipated to available for the entire study period and is capable of understanding and communicating with the investigators and clinical study facility staff. patients who agree to give written informed consent and are willing to participate in the study.

inclusion criteria: age ≥ 18 years at time of signing the informed consent form (icf). sars-cov-2 infection documented by rt-pcr within 7 days prior to randomization. hospitalized patients who meet the criteria of moderate or severe covid-19.

inclusion criteria: age ≥ 18 years at time of signing the informed consent form (icf). sars-cov-2 infection documented by rt-pcr within 7 days prior to randomization. hospitalized patients who meet the criteria of moderate or severe covid-19.