inclusion criteria: 1. ability and willingness to give written informed consent prior to any study-specific screening procedures and to comply with the requirements of the study 2. male or female, aged ≥ 18 years of age 3. diagnosed with long-covid 4. patient self-reported concerns regarding cognitive functioning or recent diagnosis of covid-19 related cognitive impairment 5. moca test scores ranging from 13 to 25/30 at screening 6. oxygen saturation spo2 ≤ 93 % on fingertip pulse oximetry and/or \< 60% on brain nirs, at rest or during effort and/ or 10% relative decrease in brain saturation during exercise as compared to baseline value at screening 7. ability to perform exercise treadmill test at screening 8. tolerability of pulsed oxygen (o2) therapy delivered by poc at screening 9. willingness and ability to wear poc.

inclusion criteria: 1. ability and willingness to give written informed consent prior to any study-specific screening procedures and to comply with the requirements of the study 2. male or female, aged ≥ 18 years of age 3. diagnosed with long-covid 4. patient self-reported concerns regarding cognitive functioning or recent diagnosis of covid-19 related cognitive impairment 5. moca test scores ranging from 13 to 25/30 at screening 6. oxygen saturation spo2 ≤ 93 % on fingertip pulse oximetry and/or \< 60% on brain nirs, at rest or during effort and/ or 10% relative decrease in brain saturation during exercise as compared to baseline value at screening 7. ability to perform exercise treadmill test at screening 8. tolerability of pulsed oxygen (o2) therapy delivered by poc at screening 9. willingness and ability to wear poc.

inclusion criteria: ability and willingness to give written informed consent prior to any study-specific screening procedures and to comply with the requirements of the study male or female, aged ≥ 18 years of age diagnosed with long-covid patient self-reported concerns regarding cognitive functioning or recent diagnosis of covid-19 related cognitive impairment moca test scores ranging from 13 to 25/30 at screening oxygen saturation spo2 ≤ 93 % on fingertip pulse oximetry and/or < 60% on brain nirs, at rest or during effort and/ or 10% relative decrease in brain saturation during exercise as compared to baseline value at screening ability to perform exercise treadmill test at screening tolerability of pulsed oxygen (o2) therapy delivered by poc at screening willingness and ability to wear poc.

inclusion criteria: ability and willingness to give written informed consent prior to any study-specific screening procedures and to comply with the requirements of the study male or female, aged ≥ 18 years of age diagnosed with long-covid patient self-reported concerns regarding cognitive functioning or recent diagnosis of covid-19 related cognitive impairment moca test scores ranging from 13 to 25/30 at screening oxygen saturation spo2 ≤ 93 % on fingertip pulse oximetry and/or < 60% on brain nirs, at rest or during effort and/ or 10% relative decrease in brain saturation during exercise as compared to baseline value at screening ability to perform exercise treadmill test at screening tolerability of pulsed oxygen (o2) therapy delivered by poc at screening willingness and ability to wear poc.