1. participant with the evidence of covid-19 infection at screening because of one or more of the following: 1. positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab) (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) 2. history of covid-19 \[step 1 only\]; 2. participant who has the history of covid-19 infection within 6 months from the first eg-covid or eg-covaro vaccination; 3. close contact with a person infected with covid-19 within 2 weeks prior to the first eg-covid or eg-covaro vaccination; 4. participants with covid-19 specific binding antibody titer 1000 iu/ml or less or over 3000 iu/ml (≤ 1000 iu/ml or \> 3000 iu/ml) measured by a specific igg enzyme-linked immunosorbent assay (elisa) \[step 2 only\]; 5. participant who is considered to have covid-19 symptoms because of one or more of the following within 2 weeks prior to the first eg-covid or eg-covaro vaccination; <!-- --> 1. according to the doctor's opinion, covid-19 is suspected as a clinical symptom; 2. history of travel outside of the country and have clinical symptoms of covid-19; 6. healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); 7. clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; 8. positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; 9. is acutely febrile or ill 72 hours prior to the first vaccination; * fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. * illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) 10. history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: <!-- --> 1. respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination 2. serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. 3. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. 4. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) 5. autoimmune diseases, including autoimmune hypothyroidism or psoriasis 6. immunodeficiency disease 7. hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator 11. history of sars-cov or mers-cov infection; 12. history of allergy or hypersensitivity reaction to any components of study vaccine; 13. history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; 14. history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) 15. history of urticaria within 5 years before the first vaccination; 16. history of hereditary or idiopathic angioneurotic edema; 17.history of organ or bone marrow transplantation; 18. history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; 19. receipt of chronic use of the following drugs within 6 months before the first vaccination: <!-- --> 1. immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. 2. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) 20. history of dependent psychotropic or opioid drug within 6 months before the first vaccination; 21. participated in an interventional clinical study except for eg-covid-102 study (step 1) within 6 months prior to the screening visit or plans to do so while participating in this study; 22. participant has been vaccinated or plan to vaccinate any within 4 weeks before/after each study vaccine; 23. participant has received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; 24. participant scheduled for surgery while participating in this study; 25. pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; 26. any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason.

1. participant with the evidence of covid-19 infection at screening because of one or more of the following: 1. positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab) (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) 2. history of covid-19 \[step 1 only\]; 2. participant who has the history of covid-19 infection within 6 months from the first eg-covid or eg-covaro vaccination; 3. close contact with a person infected with covid-19 within 2 weeks prior to the first eg-covid or eg-covaro vaccination; 4. participants with covid-19 specific binding antibody titer 1000 iu/ml or less or over 3000 iu/ml (≤ 1000 iu/ml or \> 3000 iu/ml) measured by a specific igg enzyme-linked immunosorbent assay (elisa) \[step 2 only\]; 5. participant who is considered to have covid-19 symptoms because of one or more of the following within 2 weeks prior to the first eg-covid or eg-covaro vaccination; <!-- --> 1. according to the doctor's opinion, covid-19 is suspected as a clinical symptom; 2. history of travel outside of the country and have clinical symptoms of covid-19; 6. healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); 7. clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; 8. positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; 9. is acutely febrile or ill 72 hours prior to the first vaccination; * fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. * illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) 10. history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: <!-- --> 1. respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination 2. serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. 3. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. 4. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) 5. autoimmune diseases, including autoimmune hypothyroidism or psoriasis 6. immunodeficiency disease 7. hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator 11. history of sars-cov or mers-cov infection; 12. history of allergy or hypersensitivity reaction to any components of study vaccine; 13. history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; 14. history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) 15. history of urticaria within 5 years before the first vaccination; 16. history of hereditary or idiopathic angioneurotic edema; 17.history of organ or bone marrow transplantation; 18. history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; 19. receipt of chronic use of the following drugs within 6 months before the first vaccination: <!-- --> 1. immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. 2. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) 20. history of dependent psychotropic or opioid drug within 6 months before the first vaccination; 21. participated in an interventional clinical study except for eg-covid-102 study (step 1) within 6 months prior to the screening visit or plans to do so while participating in this study; 22. participant has been vaccinated or plan to vaccinate any within 4 weeks before/after each study vaccine; 23. participant has received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; 24. participant scheduled for surgery while participating in this study; 25. pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; 26. any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason.

1. participant with the evidence of covid-19 infection at screening because of one or more of the following: positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab) (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) history of covid-19 [step 1 only]; 2. participant who has the history of covid-19 infection within 6 months from the first eg-covid or eg-covaro vaccination; 3. close contact with a person infected with covid-19 within 2 weeks prior to the first eg-covid or eg-covaro vaccination; 4. participants with covid-19 specific binding antibody titer 1000 iu/ml or less or over 3000 iu/ml (≤ 1000 iu/ml or > 3000 iu/ml) measured by a specific igg enzyme-linked immunosorbent assay (elisa) [step 2 only]; 5. participant who is considered to have covid-19 symptoms because of one or more of the following within 2 weeks prior to the first eg-covid or eg-covaro vaccination; according to the doctor's opinion, covid-19 is suspected as a clinical symptom; history of travel outside of the country and have clinical symptoms of covid-19; 6. healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); 7. clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; 8. positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; 9. is acutely febrile or ill 72 hours prior to the first vaccination; fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) 10. history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) autoimmune diseases, including autoimmune hypothyroidism or psoriasis immunodeficiency disease hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator 11. history of sars-cov or mers-cov infection; 12. history of allergy or hypersensitivity reaction to any components of study vaccine; 13. history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; 14. history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) 15. history of urticaria within 5 years before the first vaccination; 16. history of hereditary or idiopathic angioneurotic edema; 17.history of organ or bone marrow transplantation; 18. history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; 19. receipt of chronic use of the following drugs within 6 months before the first vaccination: immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) 20. history of dependent psychotropic or opioid drug within 6 months before the first vaccination; 21. participated in an interventional clinical study except for eg-covid-102 study (step 1) within 6 months prior to the screening visit or plans to do so while participating in this study; 22. participant has been vaccinated or plan to vaccinate any within 4 weeks before/after each study vaccine; 23. participant has received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; 24. participant scheduled for surgery while participating in this study; 25. pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; 26. any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason.

1. participant with the evidence of covid-19 infection at screening because of one or more of the following: positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab) (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) history of covid-19 [step 1 only]; 2. participant who has the history of covid-19 infection within 6 months from the first eg-covid or eg-covaro vaccination; 3. close contact with a person infected with covid-19 within 2 weeks prior to the first eg-covid or eg-covaro vaccination; 4. participants with covid-19 specific binding antibody titer 1000 iu/ml or less or over 3000 iu/ml (≤ 1000 iu/ml or > 3000 iu/ml) measured by a specific igg enzyme-linked immunosorbent assay (elisa) [step 2 only]; 5. participant who is considered to have covid-19 symptoms because of one or more of the following within 2 weeks prior to the first eg-covid or eg-covaro vaccination; according to the doctor's opinion, covid-19 is suspected as a clinical symptom; history of travel outside of the country and have clinical symptoms of covid-19; 6. healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); 7. clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; 8. positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; 9. is acutely febrile or ill 72 hours prior to the first vaccination; fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) 10. history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) autoimmune diseases, including autoimmune hypothyroidism or psoriasis immunodeficiency disease hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator 11. history of sars-cov or mers-cov infection; 12. history of allergy or hypersensitivity reaction to any components of study vaccine; 13. history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; 14. history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) 15. history of urticaria within 5 years before the first vaccination; 16. history of hereditary or idiopathic angioneurotic edema; 17.history of organ or bone marrow transplantation; 18. history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; 19. receipt of chronic use of the following drugs within 6 months before the first vaccination: immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) 20. history of dependent psychotropic or opioid drug within 6 months before the first vaccination; 21. participated in an interventional clinical study except for eg-covid-102 study (step 1) within 6 months prior to the screening visit or plans to do so while participating in this study; 22. participant has been vaccinated or plan to vaccinate any within 4 weeks before/after each study vaccine; 23. participant has received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; 24. participant scheduled for surgery while participating in this study; 25. pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; 26. any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason.

1. participant with the evidence of covid-19 infection at screening because of one or more of the following: positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab) (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) history of covid-19 [step 1 only]; 2. participant who has the history of covid-19 infection within 6 months from the first eg-covid or eg-covaro vaccination; 3. close contact with a person infected with covid-19 within 2 weeks prior to the first eg-covid or eg-covaro vaccination; 4. participants with high covid-19 specific binding antibody titer more than 1000 iu/ml measured by a specific igg enzyme-linked immunosorbent assay (elisa) [step 2 only]; 5. participant who is considered to have covid-19 symptoms because of one or more of the following within 2 weeks prior to the first eg-covid or eg-covaro vaccination; according to the doctor's opinion, covid-19 is suspected as a clinical symptom; history of travel outside of the country and have clinical symptoms of covid-19; 6. healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); 7. clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; 8. positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; 9. is acutely febrile or ill 72 hours prior to the first vaccination; fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) 10. history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) autoimmune diseases, including autoimmune hypothyroidism or psoriasis immunodeficiency disease hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator 11. history of sars-cov or mers-cov infection; 12. history of allergy or hypersensitivity reaction to any components of study vaccine; 13. history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; 14. history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) 15. history of urticaria within 5 years before the first vaccination; 16. history of hereditary or idiopathic angioneurotic edema; 17.history of organ or bone marrow transplantation; 18. history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; 19. receipt of chronic use of the following drugs within 6 months before the first vaccination: immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) 20. history of dependent psychotropic or opioid drug within 6 months before the first vaccination; 21. participated in an interventional clinical study except for eg-covid-102 study (step 1) within 6 months prior to the screening visit or plans to do so while participating in this study; 22. participant has been vaccinated or plan to vaccinate any within 4 weeks before/after each study vaccine; 23. participant has received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; 24. participant scheduled for surgery while participating in this study; 25. pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; 26. any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason.

1. participant with the evidence of covid-19 infection at screening because of one or more of the following: positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab) (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) history of covid-19 [step 1 only]; 2. participant who has the history of covid-19 infection within 6 months from the first eg-covid or eg-covaro vaccination; 3. close contact with a person infected with covid-19 within 2 weeks prior to the first eg-covid or eg-covaro vaccination; 4. participants with high covid-19 specific binding antibody titer more than 1000 iu/ml measured by a specific igg enzyme-linked immunosorbent assay (elisa) [step 2 only]; 5. participant who is considered to have covid-19 symptoms because of one or more of the following within 2 weeks prior to the first eg-covid or eg-covaro vaccination; according to the doctor's opinion, covid-19 is suspected as a clinical symptom; history of travel outside of the country and have clinical symptoms of covid-19; 6. healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); 7. clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; 8. positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; 9. is acutely febrile or ill 72 hours prior to the first vaccination; fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) 10. history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) autoimmune diseases, including autoimmune hypothyroidism or psoriasis immunodeficiency disease hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator 11. history of sars-cov or mers-cov infection; 12. history of allergy or hypersensitivity reaction to any components of study vaccine; 13. history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; 14. history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) 15. history of urticaria within 5 years before the first vaccination; 16. history of hereditary or idiopathic angioneurotic edema; 17.history of organ or bone marrow transplantation; 18. history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; 19. receipt of chronic use of the following drugs within 6 months before the first vaccination: immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) 20. history of dependent psychotropic or opioid drug within 6 months before the first vaccination; 21. participated in an interventional clinical study except for eg-covid-102 study (step 1) within 6 months prior to the screening visit or plans to do so while participating in this study; 22. participant has been vaccinated or plan to vaccinate any within 4 weeks before/after each study vaccine; 23. participant has received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; 24. participant scheduled for surgery while participating in this study; 25. pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; 26. any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason.

participant with the evidence of covid-19 infection because of one or more of the following: positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab), (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) history of covid-19; close contact with a person infected with covid-19 or have been classified as symptomatic* person to covid-19 within 14 days prior to the first vaccination; * symptomatic person according to the doctor's opinion, covid-19 is suspected as a clinical symptom; history of travel outside of the country and have clinical symptoms of covid-19 within 14 days of return; healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; is acutely febrile or ill 72 hours prior to the first vaccination; fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) autoimmune diseases, including autoimmune hypothyroidism or psoriasis immunodeficiency disease hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator history of sars-cov or mers-cov infection; history of allergy or hypersensitivity reaction to any components of study vaccine; history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) history of urticarial within 5 years before the first vaccination; history of hereditary or idiopathic angioneurotic edema; history of organ or bone marrow transplantation; history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; (step ii only) previous vaccination history of *mrna based covid-19 vaccine prior administration of an investigational substance vaccine receipt of chronic use of the following drugs within 6 months before the first vaccination: immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) history of dependent psychotropic or opioid drug within 6 months before the first vaccination; participated in an interventional clinical study within 6 months prior to the screening visit or plans to do so while participating in this study; participants have been vaccinated or plan to vaccinate within 4 weeks before/after each vaccination; participants have received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; participants scheduled for surgery while participating in this study; pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason. any kinds of covid-19 vaccination history are allowed for step i, but each covid-19 vaccination history is allowed for step ii except mrna based covid-19 vaccine. ip should be vaccinated to subject minimal 3 months after last vaccination of previous covid-19 vaccine.

participant with the evidence of covid-19 infection because of one or more of the following: positive for covid-19 when performing rt-pcr with upper respiratory tract samples; (oropharyngeal/nasopharyngeal swab), (however, if symptoms of cough or sputum are present, additional rt-pcr is performed using a lower respiratory tract sample (sputum), and registration is possible if all are negative) history of covid-19; close contact with a person infected with covid-19 or have been classified as symptomatic* person to covid-19 within 14 days prior to the first vaccination; * symptomatic person according to the doctor's opinion, covid-19 is suspected as a clinical symptom; history of travel outside of the country and have clinical symptoms of covid-19 within 14 days of return; healthcare workers who can participate in the treatment of covid-19 patients, or those at high risk of exposure to sars-cov-2 (screening clinics and emergency room workers, workers related to covid-19 prevention, workers involved in collecting or analysing covid-19 samples, etc.); clinically significant abnormalities in laboratory tests, electrocardiogram (ecg), or chest x-rays performed at the screening; positive test for hepatitis c antibody (hcv), hepatitis b surface antigen (hbsag), human immunodeficiency virus (hiv) antibody, or syphilis antibody at screening; is acutely febrile or ill 72 hours prior to the first vaccination; fever is defined as a body temperature ≥38.0°celsius / ≥100.4°farenheit. illness is defined as symptoms due to other infectious diseases (cough, shortness of breath, chills, muscle pain, headache, sore throat, loss of smell, or loss of taste, etc.) history of a diagnosis or condition that, in the judgment of the investigator, may affect study endpoint assessment or participant safety, specifically: respiratory system: asthma, chronic obstructive pulmonary disease (copd), daily medication administration for active tuberculosis or latent tuberculosis, received treatment due to worsening of respiratory diseases within 5 years prior to the first vaccination serious cardiovascular disease: congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension, myocarditis, pericarditis, etc. nervous system: epilepsy, seizure (within 3 years before the first vaccination), migraine, stroke, encephalopathy, guillain-barré syndrome, encephalomyelitis, transverse myelitis, etc. diagnosis of malignancy within the previous 10 years before the first vaccination (except basal cell and squamous cell carcinoma) autoimmune diseases, including autoimmune hypothyroidism or psoriasis immunodeficiency disease hepatobiliary, renal, endocrine, urinary, musculoskeletal or other disorders judged to be clinically significant by the investigator history of sars-cov or mers-cov infection; history of allergy or hypersensitivity reaction to any components of study vaccine; history of serious adverse reaction, allergy or hypersensitivity reaction to any vaccination; history of platelet-related disease or hemorrhagic disease, or have a history of severe bleeding or bruising after intramuscular injection (im) or venipuncture, or are taking anticoagulants; (however, according to the judgment of the investigators, there can be involved when using a low dose of an anticoagulant (eg, aspirin at 100mg/day or less)) history of urticarial within 5 years before the first vaccination; history of hereditary or idiopathic angioneurotic edema; history of organ or bone marrow transplantation; history or suspicion of illegal substance use or alcohol abuse within the past 6 months before the first vaccination; (step ii only) previous vaccination history of *mrna based covid-19 vaccine prior administration of an investigational substance vaccine receipt of chronic use of the following drugs within 6 months before the first vaccination: immunosuppressants and immunomodulators: azathioprine, cyclosporine, interferon, g-csf, tacrolimus, everolimus, sirolimus, cyclophosphamide, 6-mercaptopurine, methotrexate, rapamycin, leflunomide, etc. systemic steroids: when a dose exceeding 10 mg/day and has been used for more than 14 consecutive days based on prednisolone (however, external steroids, nasal sprays, inhalants, and eye drops are permitted regardless of the dosage) history of dependent psychotropic or opioid drug within 6 months before the first vaccination; participated in an interventional clinical study within 6 months prior to the screening visit or plans to do so while participating in this study; participants have been vaccinated or plan to vaccinate within 4 weeks before/after each vaccination; participants have received immunoglobulin or blood-derived products within 3 months prior to the first vaccination, or those who plan to administer it during the study; participants scheduled for surgery while participating in this study; pregnant or lactating at screening or planning to become pregnant (self or partner) at any time during the study, including the follow-up period; any other reason that, in the opinion of the investigator, unlikely to comply with the clinical study protocol or is unsuitable for any other reason. any kinds of covid-19 vaccination history are allowed for step i, but each covid-19 vaccination history is allowed for step ii except mrna based covid-19 vaccine. ip should be vaccinated to subject minimal 3 months after last vaccination of previous covid-19 vaccine.