inclusion criteria: * patients hospitalized in the icu with severe acute respiratory syndrome * progressive deterioration of the ventilatory status in the first 48 hours in the icu, which may require mechanical ventilation within this period; * confirmed diagnosis of covid-19 within 3 days of icu admission; * acceptance to participate.

inclusion criteria: * patients hospitalized in the icu with severe acute respiratory syndrome * progressive deterioration of the ventilatory status in the first 48 hours in the icu, which may require mechanical ventilation within this period; * confirmed diagnosis of covid-19 within 3 days of icu admission; * acceptance to participate.

inclusion criteria: patients hospitalized in the icu with severe acute respiratory syndrome progressive deterioration of the ventilatory status in the first 48 hours in the icu, which may require mechanical ventilation within this period; confirmed diagnosis of covid-19 within 3 days of icu admission; acceptance to participate.

inclusion criteria: patients hospitalized in the icu with severe acute respiratory syndrome progressive deterioration of the ventilatory status in the first 48 hours in the icu, which may require mechanical ventilation within this period; confirmed diagnosis of covid-19 within 3 days of icu admission; acceptance to participate.