inclusion criteria: 1. male and female patients from 18 to 85 years of age. 2. the patient (or his/her legal representative, if the patient is not able to sign the form) signed an informed consent form for participation in this study before any initiation of any study procedures. 3. the patient can understand all protocol requirements, perform the study procedures, and agree to all limitations specified in the protocol. 4. confirmed diagnosis of coronavirus disease (covid-19): laboratory-confirmed sars-cov-2 infection as determined by pcr, or other commercial or public health assay in any specimen \< 14 days prior to randomization. 5. illness (coronavirus disease covid-19) of any duration, and at least one of the following: * radiographic/tomographic chest infiltrates by imaging (chest x-ray, ct scan, etc.), or * evidence of rales/crackles on clinical exam and spo2 ≤ 94% on room air, or * indications for mechanical ventilation and/or supplemental oxygen. 6. agrees to use adequate contraception methods (the methods with at least 90% efficacy include non-hormonal intrauterine devices; condom with intravaginal spermicide; cervical caps

inclusion criteria: 1. male and female patients from 18 to 85 years of age. 2. the patient (or his/her legal representative, if the patient is not able to sign the form) signed an informed consent form for participation in this study before any initiation of any study procedures. 3. the patient can understand all protocol requirements, perform the study procedures, and agree to all limitations specified in the protocol. 4. confirmed diagnosis of coronavirus disease (covid-19): laboratory-confirmed sars-cov-2 infection as determined by pcr, or other commercial or public health assay in any specimen \< 14 days prior to randomization. 5. illness (coronavirus disease covid-19) of any duration, and at least one of the following: * radiographic/tomographic chest infiltrates by imaging (chest x-ray, ct scan, etc.), or * evidence of rales/crackles on clinical exam and spo2 ≤ 94% on room air, or * indications for mechanical ventilation and/or supplemental oxygen. 6. agrees to use adequate contraception methods (the methods with at least 90% efficacy include non-hormonal intrauterine devices; condom with intravaginal spermicide; cervical caps

inclusion criteria: male and female patients from 18 to 85 years of age. the patient (or his/her legal representative, if the patient is not able to sign the form) signed an informed consent form for participation in this study before any initiation of any study procedures. the patient can understand all protocol requirements, perform the study procedures, and agree to all limitations specified in the protocol. confirmed diagnosis of coronavirus disease (covid-19): laboratory-confirmed sars-cov-2 infection as determined by pcr, or other commercial or public health assay in any specimen < 14 days prior to randomization. illness (coronavirus disease covid-19) of any duration, and at least one of the following: radiographic/tomographic chest infiltrates by imaging (chest x-ray, ct scan, etc.), or evidence of rales/crackles on clinical exam and spo2 ≤ 94% on room air, or indications for mechanical ventilation and/or supplemental oxygen. agrees to use adequate contraception methods (the methods with at least 90% efficacy include non-hormonal intrauterine devices; condom with intravaginal spermicide; cervical caps

inclusion criteria: male and female patients from 18 to 85 years of age. the patient (or his/her legal representative, if the patient is not able to sign the form) signed an informed consent form for participation in this study before any initiation of any study procedures. the patient can understand all protocol requirements, perform the study procedures, and agree to all limitations specified in the protocol. confirmed diagnosis of coronavirus disease (covid-19): laboratory-confirmed sars-cov-2 infection as determined by pcr, or other commercial or public health assay in any specimen < 14 days prior to randomization. illness (coronavirus disease covid-19) of any duration, and at least one of the following: radiographic/tomographic chest infiltrates by imaging (chest x-ray, ct scan, etc.), or evidence of rales/crackles on clinical exam and spo2 ≤ 94% on room air, or indications for mechanical ventilation and/or supplemental oxygen. agrees to use adequate contraception methods (the methods with at least 90% efficacy include non-hormonal intrauterine devices; condom with intravaginal spermicide; cervical caps

inclusion criteria: 1. male and female patients from 18 to 85 years of age. 2. the patient (or his/her legal representative, if the patient is not able to sign the form) signed an informed consent form for participation in this study before any initiation of any study procedures. 3. the patient can understand all protocol requirements, perform the study procedures, and agree to all limitations specified in the protocol. 4. confirmed diagnosis of coronavirus disease (covid-19): laboratory-confirmed sars-cov-2 infection as determined by pcr, or other commercial or public health assay in any specimen < 14 days prior to randomization. 5. illness (coronavirus disease covid-19) of any duration, and at least one of the following: - radiographic/tomographic chest infiltrates by imaging (chest x-ray, ct scan, etc.), or - evidence of rales/crackles on clinical exam and spo2 ≤ 94% on room air, or - indications for mechanical ventilation and/or supplemental oxygen. 6. agrees to use adequate contraception methods (the methods with at least 90% efficacy include non-hormonal intrauterine devices; condom with intravaginal spermicide; cervical caps

inclusion criteria: 1. male and female patients from 18 to 85 years of age. 2. the patient (or his/her legal representative, if the patient is not able to sign the form) signed an informed consent form for participation in this study before any initiation of any study procedures. 3. the patient can understand all protocol requirements, perform the study procedures, and agree to all limitations specified in the protocol. 4. confirmed diagnosis of coronavirus disease (covid-19): laboratory-confirmed sars-cov-2 infection as determined by pcr, or other commercial or public health assay in any specimen < 14 days prior to randomization. 5. illness (coronavirus disease covid-19) of any duration, and at least one of the following: - radiographic/tomographic chest infiltrates by imaging (chest x-ray, ct scan, etc.), or - evidence of rales/crackles on clinical exam and spo2 ≤ 94% on room air, or - indications for mechanical ventilation and/or supplemental oxygen. 6. agrees to use adequate contraception methods (the methods with at least 90% efficacy include non-hormonal intrauterine devices; condom with intravaginal spermicide; cervical caps