inclusion criteria: * hospitalization with moderate to severe covid-19, defined as fulfilling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" \[oxygen via mask or nasal\] * laboratory-confirmed sars-cov-2 infection at index hospitalisation as determined by pcr or other validated commercial or public health assay * bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) * dpp3 ≤30 ng/ml * age ≥18 years at time of screening * body weight ≤ 150 kg at time of screening

inclusion criteria: * hospitalization with moderate to severe covid-19, defined as fulfilling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" \[oxygen via mask or nasal\] * laboratory-confirmed sars-cov-2 infection at index hospitalisation as determined by pcr or other validated commercial or public health assay * bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) * dpp3 ≤30 ng/ml * age ≥18 years at time of screening * body weight ≤ 150 kg at time of screening

inclusion criteria: hospitalization with moderate to severe covid-19, defined as fulfilling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" [oxygen via mask or nasal] laboratory-confirmed sars-cov-2 infection at index hospitalisation as determined by pcr or other validated commercial or public health assay bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) dpp3 ≤30 ng/ml age ≥18 years at time of screening body weight ≤ 150 kg at time of screening

inclusion criteria: hospitalization with moderate to severe covid-19, defined as fulfilling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" [oxygen via mask or nasal] laboratory-confirmed sars-cov-2 infection at index hospitalisation as determined by pcr or other validated commercial or public health assay bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) dpp3 ≤30 ng/ml age ≥18 years at time of screening body weight ≤ 150 kg at time of screening

inclusion criteria: hospitalization for moderate to severe covid-19, defined as ful-filling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" [oxygen via mask or nasal] laboratory-confirmed sars-cov-2 infection at index hospitalisation as determined by pcr or other validated commercial or public health assay bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) dpp3 ≤50 ng/ml age ≥18 years at time of screening body weight ≤ 150 kg at time of screening

inclusion criteria: hospitalization for moderate to severe covid-19, defined as ful-filling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" [oxygen via mask or nasal] laboratory-confirmed sars-cov-2 infection at index hospitalisation as determined by pcr or other validated commercial or public health assay bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) dpp3 ≤50 ng/ml age ≥18 years at time of screening body weight ≤ 150 kg at time of screening

inclusion criteria: hospitalization for moderate to severe covid-19, defined as ful-filling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" [oxygen via mask or nasal] bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) dpp3 ≤50 ng/ml age ≥18 years at time of screening body weight ≤ 150 kg at time of screening

inclusion criteria: hospitalization for moderate to severe covid-19, defined as ful-filling at a minimum the following clinical status category on the who 8-point ordinal scale: (i) "score 4" [oxygen via mask or nasal] bio-adm ≥50 pg/ml or ≥30% increase until the end of the next day (with a minimum of 35 pg/ml at all) dpp3 ≤50 ng/ml age ≥18 years at time of screening body weight ≤ 150 kg at time of screening