inclusion criteria: * people aged 18-60 years (both inclusive) for phase 1 and aged ≥18 years for phase 2； * medical history and physical examination indicating as a healthy person; * the female participant or the spouse (or partner) of the male participant in child-birthing age agrees to use effective contraceptive measure throughout the whole course of this clinical trial. * those who are participating in this clinical trial voluntarily, have signed the informed consent form, and been able to understand and comply with the requirements of the clinical trial protocol.

inclusion criteria: * people aged 18-60 years (both inclusive) for phase 1 and aged ≥18 years for phase 2； * medical history and physical examination indicating as a healthy person; * the female participant or the spouse (or partner) of the male participant in child-birthing age agrees to use effective contraceptive measure throughout the whole course of this clinical trial. * those who are participating in this clinical trial voluntarily, have signed the informed consent form, and been able to understand and comply with the requirements of the clinical trial protocol.

inclusion criteria: people aged 18-60 years (both inclusive) for phase 1 and aged ≥18 years for phase 2； medical history and physical examination indicating as a healthy person; the female participant or the spouse (or partner) of the male participant in child-birthing age agrees to use effective contraceptive measure throughout the whole course of this clinical trial. those who are participating in this clinical trial voluntarily, have signed the informed consent form, and been able to understand and comply with the requirements of the clinical trial protocol.

inclusion criteria: people aged 18-60 years (both inclusive) for phase 1 and aged ≥18 years for phase 2； medical history and physical examination indicating as a healthy person; the female participant or the spouse (or partner) of the male participant in child-birthing age agrees to use effective contraceptive measure throughout the whole course of this clinical trial. those who are participating in this clinical trial voluntarily, have signed the informed consent form, and been able to understand and comply with the requirements of the clinical trial protocol.