inclusion criteria: 1. any gender 2. age 18 and older 3. informed consent for participation in the study 4. virological diagnosis of sars-cov2 infection (pcr) 5. acute respiratory failure 6. radiographic pneumonia, defined as any/ changing new lung infiltrate 7. patient breathing spontaneously, required more than 50% oxygen and mews score \> 7. 8. if intubated, intubated less than 24 hours with pao2/fio2 ratio ≤ 200 and peep ≥ 5 cm h2o.

inclusion criteria: 1. any gender 2. age 18 and older 3. informed consent for participation in the study 4. virological diagnosis of sars-cov2 infection (pcr) 5. acute respiratory failure 6. radiographic pneumonia, defined as any/ changing new lung infiltrate 7. patient breathing spontaneously, required more than 50% oxygen and mews score \> 7. 8. if intubated, intubated less than 24 hours with pao2/fio2 ratio ≤ 200 and peep ≥ 5 cm h2o.

inclusion criteria: any gender age 18 and older informed consent for participation in the study virological diagnosis of sars-cov2 infection (pcr) acute respiratory failure radiographic pneumonia, defined as any/ changing new lung infiltrate patient breathing spontaneously, required more than 50% oxygen and mews score > 7. if intubated, intubated less than 24 hours with pao2/fio2 ratio ≤ 200 and peep ≥ 5 cm h2o.

inclusion criteria: any gender age 18 and older informed consent for participation in the study virological diagnosis of sars-cov2 infection (pcr) acute respiratory failure radiographic pneumonia, defined as any/ changing new lung infiltrate patient breathing spontaneously, required more than 50% oxygen and mews score > 7. if intubated, intubated less than 24 hours with pao2/fio2 ratio ≤ 200 and peep ≥ 5 cm h2o.

inclusion criteria: 1. any gender 2. age 18 and older 3. informed consent for participation in the study 4. virological diagnosis of sars-cov2 infection (pcr) 5. acute respiratory failure 6. radiographic pneumonia, defined as any/ changing new lung infiltrate 7. patient breathing spontaneously, required more than 50% oxygen and mews score > 7. 8. if intubated, intubated less than 24 hours with pao2/fio2 ratio ≤ 200 and peep ≥ 5 cm h2o.

inclusion criteria: 1. any gender 2. age 18 and older 3. informed consent for participation in the study 4. virological diagnosis of sars-cov2 infection (pcr) 5. acute respiratory failure 6. radiographic pneumonia, defined as any/ changing new lung infiltrate 7. patient breathing spontaneously, required more than 50% oxygen and mews score > 7. 8. if intubated, intubated less than 24 hours with pao2/fio2 ratio ≤ 200 and peep ≥ 5 cm h2o.