inclusion criteria: 1. male or female subject ≥18 years and \< 80 years of age; 2. subjects with diagnosis of covid-19 disease by pcr in nasopharyngeal smear, sputum, or bronchial aspirates; 3. subjects admitted in icu with invasive mechanical ventilation; 4. informed consent granted via telephone by relatives or legal representative

inclusion criteria: 1. male or female subject ≥18 years and \< 80 years of age; 2. subjects with diagnosis of covid-19 disease by pcr in nasopharyngeal smear, sputum, or bronchial aspirates; 3. subjects admitted in icu with invasive mechanical ventilation; 4. informed consent granted via telephone by relatives or legal representative

inclusion criteria: male or female subject ≥18 years and < 80 years of age; subjects with diagnosis of covid-19 disease by pcr in nasopharyngeal smear, sputum, or bronchial aspirates; subjects admitted in icu with invasive mechanical ventilation; informed consent granted via telephone by relatives or legal representative

inclusion criteria: male or female subject ≥18 years and < 80 years of age; subjects with diagnosis of covid-19 disease by pcr in nasopharyngeal smear, sputum, or bronchial aspirates; subjects admitted in icu with invasive mechanical ventilation; informed consent granted via telephone by relatives or legal representative

inclusion criteria: 1. male or female subject ≥18 years and < 80 years of age; 2. subjects with diagnosis of covid-19 disease by pcr in nasopharyngeal smear, sputum, or bronchial aspirates; 3. subjects admitted in icu with invasive mechanical ventilation; 4. informed consent granted via telephone by relatives or legal representative

inclusion criteria: 1. male or female subject ≥18 years and < 80 years of age; 2. subjects with diagnosis of covid-19 disease by pcr in nasopharyngeal smear, sputum, or bronchial aspirates; 3. subjects admitted in icu with invasive mechanical ventilation; 4. informed consent granted via telephone by relatives or legal representative