1. ast or alt 2 \> x upper limit of normal. 2. abnormal bilirubin (total bilirubin \> 1.2 mg/dl, direct bilirubin \> 0.4 mg/dl) 3. creatinine \> 2.0 mg/dl. 4. known coronary artery disease or ekg suggestive of coronary artery disease unless cardiac clearance for apheresis is obtained from a cardiologist. 5. known active infection such as hepatitis b, hepatitis c, or human immunodeficiency virus (hiv) 6. pregnancy assessed by a positive serum pregnancy test or breastfeeding mothers 7. use of immunosuppressive medication within one month of enrollment including but not limited to cyclosporine, tacrolimus, sirolimus, and chemotherapy. 8. anticoagulation other than asa. 9. hemoglobin \< 10 g/dl or platelets \< 100 k/ml 10. is unable or unwilling to provide informed consent 11. presence of any other physical or psychological medical condition that, in the opinion of the investigator, would preclude participation

1. ast or alt 2 \> x upper limit of normal. 2. abnormal bilirubin (total bilirubin \> 1.2 mg/dl, direct bilirubin \> 0.4 mg/dl) 3. creatinine \> 2.0 mg/dl. 4. known coronary artery disease or ekg suggestive of coronary artery disease unless cardiac clearance for apheresis is obtained from a cardiologist. 5. known active infection such as hepatitis b, hepatitis c, or human immunodeficiency virus (hiv) 6. pregnancy assessed by a positive serum pregnancy test or breastfeeding mothers 7. use of immunosuppressive medication within one month of enrollment including but not limited to cyclosporine, tacrolimus, sirolimus, and chemotherapy. 8. anticoagulation other than asa. 9. hemoglobin \< 10 g/dl or platelets \< 100 k/ml 10. is unable or unwilling to provide informed consent 11. presence of any other physical or psychological medical condition that, in the opinion of the investigator, would preclude participation

ast or alt 2 > x upper limit of normal. abnormal bilirubin (total bilirubin > 1.2 mg/dl, direct bilirubin > 0.4 mg/dl) creatinine > 2.0 mg/dl. known coronary artery disease or ekg suggestive of coronary artery disease unless cardiac clearance for apheresis is obtained from a cardiologist. known active infection such as hepatitis b, hepatitis c, or human immunodeficiency virus (hiv) pregnancy assessed by a positive serum pregnancy test or breastfeeding mothers use of immunosuppressive medication within one month of enrollment including but not limited to cyclosporine, tacrolimus, sirolimus, and chemotherapy. anticoagulation other than asa. hemoglobin < 10 g/dl or platelets < 100 k/ml is unable or unwilling to provide informed consent presence of any other physical or psychological medical condition that, in the opinion of the investigator, would preclude participation

ast or alt 2 > x upper limit of normal. abnormal bilirubin (total bilirubin > 1.2 mg/dl, direct bilirubin > 0.4 mg/dl) creatinine > 2.0 mg/dl. known coronary artery disease or ekg suggestive of coronary artery disease unless cardiac clearance for apheresis is obtained from a cardiologist. known active infection such as hepatitis b, hepatitis c, or human immunodeficiency virus (hiv) pregnancy assessed by a positive serum pregnancy test or breastfeeding mothers use of immunosuppressive medication within one month of enrollment including but not limited to cyclosporine, tacrolimus, sirolimus, and chemotherapy. anticoagulation other than asa. hemoglobin < 10 g/dl or platelets < 100 k/ml is unable or unwilling to provide informed consent presence of any other physical or psychological medical condition that, in the opinion of the investigator, would preclude participation

1. ast or alt 2 > x upper limit of normal. 2. abnormal bilirubin (total bilirubin > 1.2 mg/dl, direct bilirubin > 0.4 mg/dl) 3. creatinine > 2.0 mg/dl. 4. known coronary artery disease or ekg suggestive of coronary artery disease unless cardiac clearance for apheresis is obtained from a cardiologist. 5. known active infection such as hepatitis b, hepatitis c, or human immunodeficiency virus (hiv) 6. pregnancy assessed by a positive serum pregnancy test or breastfeeding mothers 7. use of immunosuppressive medication within one month of enrollment including but not limited to cyclosporine, tacrolimus, sirolimus, and chemotherapy. 8. anticoagulation other than asa. 9. hemoglobin < 10 g/dl or platelets < 100 k/ml 10. is unable or unwilling to provide informed consent 11. presence of any other physical or psychological medical condition that, in the opinion of the investigator, would preclude participation

1. ast or alt 2 > x upper limit of normal. 2. abnormal bilirubin (total bilirubin > 1.2 mg/dl, direct bilirubin > 0.4 mg/dl) 3. creatinine > 2.0 mg/dl. 4. known coronary artery disease or ekg suggestive of coronary artery disease unless cardiac clearance for apheresis is obtained from a cardiologist. 5. known active infection such as hepatitis b, hepatitis c, or human immunodeficiency virus (hiv) 6. pregnancy assessed by a positive serum pregnancy test or breastfeeding mothers 7. use of immunosuppressive medication within one month of enrollment including but not limited to cyclosporine, tacrolimus, sirolimus, and chemotherapy. 8. anticoagulation other than asa. 9. hemoglobin < 10 g/dl or platelets < 100 k/ml 10. is unable or unwilling to provide informed consent 11. presence of any other physical or psychological medical condition that, in the opinion of the investigator, would preclude participation