inclusion criteria: * admitted covid 19 patients to the icu with the following criteria : : * hypoxia (p/f less than 100) * need for high level of oxygenation or ventilatory support * tachypnea, respiratory distress due to hypoxia * \>50 percent involvement of the lung parenchyma on chest imaging . * serum il-6 ≥ 5 x upper normal limit of daily increase of \>1 time * ferritin \>300 ug/l with doubling within 24 hours * ferritin \>600 ug/l at presentation * ldh \>250 u/l * elevated d-dimer (\>1 mg/l)

inclusion criteria: * admitted covid 19 patients to the icu with the following criteria : : * hypoxia (p/f less than 100) * need for high level of oxygenation or ventilatory support * tachypnea, respiratory distress due to hypoxia * \>50 percent involvement of the lung parenchyma on chest imaging . * serum il-6 ≥ 5 x upper normal limit of daily increase of \>1 time * ferritin \>300 ug/l with doubling within 24 hours * ferritin \>600 ug/l at presentation * ldh \>250 u/l * elevated d-dimer (\>1 mg/l)

inclusion criteria: - admitted covid 19 patients to the icu with the following criteria : : - hypoxia (p/f less than 100) - need for high level of oxygenation or ventilatory support - tachypnea, respiratory distress due to hypoxia - >50 percent involvement of the lung parenchyma on chest imaging . - serum il-6 ≥ 5 x upper normal limit of daily increase of >1 time - ferritin >300 ug/l with doubling within 24 hours - ferritin >600 ug/l at presentation - ldh >250 u/l - elevated d-dimer (>1 mg/l)

inclusion criteria: - admitted covid 19 patients to the icu with the following criteria : : - hypoxia (p/f less than 100) - need for high level of oxygenation or ventilatory support - tachypnea, respiratory distress due to hypoxia - >50 percent involvement of the lung parenchyma on chest imaging . - serum il-6 ≥ 5 x upper normal limit of daily increase of >1 time - ferritin >300 ug/l with doubling within 24 hours - ferritin >600 ug/l at presentation - ldh >250 u/l - elevated d-dimer (>1 mg/l)