inclusion criteria: * man or woman \> 45 years old. * patient with a positive sars-cov-2 pcr * patient with ent and / or respiratory symptoms, without hospitalization criteria (no dyspnea, respiratory rate \<22 / min, sao2 ≥ 94% in ambient air), or digestive signs. * patient with at least one of the following risk factors for unfavorable outcome: * 70 years, bmi\> 30, cardiovascular history (stroke, coronary artery disease, complicated hypertension, cardiac surgery, nyha iii or iv heart failure), respiratory pathology likely to decompensate during viral infection respiratory failure, unbalanced and / or complicated diabètes, respiratory pathology likely to decompensate in the event of of viral infection, patients with renal insufficiency chronic dialysis, .cancer patients under treatment.

inclusion criteria: * man or woman \> 45 years old. * patient with a positive sars-cov-2 pcr * patient with ent and / or respiratory symptoms, without hospitalization criteria (no dyspnea, respiratory rate \<22 / min, sao2 ≥ 94% in ambient air), or digestive signs. * patient with at least one of the following risk factors for unfavorable outcome: * 70 years, bmi\> 30, cardiovascular history (stroke, coronary artery disease, complicated hypertension, cardiac surgery, nyha iii or iv heart failure), respiratory pathology likely to decompensate during viral infection respiratory failure, unbalanced and / or complicated diabètes, respiratory pathology likely to decompensate in the event of of viral infection, patients with renal insufficiency chronic dialysis, .cancer patients under treatment.

inclusion criteria: - man or woman > 45 years old. - patient with a positive sars-cov-2 pcr - patient with ent and / or respiratory symptoms, without hospitalization criteria (no dyspnea, respiratory rate <22 / min, sao2 ≥ 94% in ambient air), or digestive signs. - patient with at least one of the following risk factors for unfavorable outcome: - 70 years, bmi> 30, cardiovascular history (stroke, coronary artery disease, complicated hypertension, cardiac surgery, nyha iii or iv heart failure), respiratory pathology likely to decompensate during viral infection respiratory failure, unbalanced and / or complicated diabètes, respiratory pathology likely to decompensate in the event of of viral infection, patients with renal insufficiency chronic dialysis, .cancer patients under treatment.

inclusion criteria: - man or woman > 45 years old. - patient with a positive sars-cov-2 pcr - patient with ent and / or respiratory symptoms, without hospitalization criteria (no dyspnea, respiratory rate <22 / min, sao2 ≥ 94% in ambient air), or digestive signs. - patient with at least one of the following risk factors for unfavorable outcome: - 70 years, bmi> 30, cardiovascular history (stroke, coronary artery disease, complicated hypertension, cardiac surgery, nyha iii or iv heart failure), respiratory pathology likely to decompensate during viral infection respiratory failure, unbalanced and / or complicated diabètes, respiratory pathology likely to decompensate in the event of of viral infection, patients with renal insufficiency chronic dialysis, .cancer patients under treatment.