* contraindication to transfusion due to inability to tolerate additional fluid, such as due to decompensated congestive heart failure. * history of previous severe allergic reactions to transfused blood products. * limiting comorbidity for administering the therapies provided for in this protocol in the opinion of the investigator. * not currently enrolled another interventional clinical trial of covid-19 treatment. * critically ill patient with covid-19 being treated in intensive care.

* contraindication to transfusion due to inability to tolerate additional fluid, such as due to decompensated congestive heart failure. * history of previous severe allergic reactions to transfused blood products. * limiting comorbidity for administering the therapies provided for in this protocol in the opinion of the investigator. * not currently enrolled another interventional clinical trial of covid-19 treatment. * critically ill patient with covid-19 being treated in intensive care.

- contraindication to transfusion due to inability to tolerate additional fluid, such as due to decompensated congestive heart failure. - history of previous severe allergic reactions to transfused blood products. - limiting comorbidity for administering the therapies provided for in this protocol in the opinion of the investigator. - not currently enrolled another interventional clinical trial of covid-19 treatment. - critically ill patient with covid-19 being treated in intensive care.

- contraindication to transfusion due to inability to tolerate additional fluid, such as due to decompensated congestive heart failure. - history of previous severe allergic reactions to transfused blood products. - limiting comorbidity for administering the therapies provided for in this protocol in the opinion of the investigator. - not currently enrolled another interventional clinical trial of covid-19 treatment. - critically ill patient with covid-19 being treated in intensive care.