* have had any acute illness with or without fever, within 72 hours prior to the first vaccination * symptoms of upper respiratory infection, fever, persistent cough, shortness of breath, runny nose and breathing difficulties * breastfeeding or who plan to breastfeed during the study * have a known allergy, hypersensitivity, or intolerance to aminoglycosides * had any clinically significant or chronic medical condition or any major surgery within the past 5 years which * have any surgery planned during the study * had any chronic use of any systemic medications, including immunosuppressant's, oral corticosteroids or other immune-modifying drugs, within the 12 months prior to screening * received any vaccination within the 28 days prior to screening * received any prescription medicines (except hormonal contraception for wocbp) within 14 days prior to visit 0 (screening) or over the counter medicines (except paracetamol and acetaminophen at a dose of (≤2 grams/day)) within 48 hours of visit 0. * have a known history or a positive test of hiv 1 or 2, hep b, or hep c * have a positive rtpcr test for sars-cov-2 within 2 days of screening * documented history of previous infection with sars-cov-2 and/or who have the presence of serum ab indicative of a previous sars-cov-2 infection * have a history of hypersensitivity or have had a serious reaction to a previous vaccination * have any abnormality or permanent body art (eg, tattoo) that, would obstruct the ability to observe local reactions at the injection site. * have a condition known to put them at high risk for severe covid-19, including those with any of the following risk factors: hypertension, diabetes mellitus, chronic pulmonary disease, asthma, chronic liver disease, known stage 3 or worse chronic kidney disease * anticipating the need for immunosuppressive treatment within the next 6 months. other inclusion or exclusion criteria may apply.

* have had any acute illness with or without fever, within 72 hours prior to the first vaccination * symptoms of upper respiratory infection, fever, persistent cough, shortness of breath, runny nose and breathing difficulties * breastfeeding or who plan to breastfeed during the study * have a known allergy, hypersensitivity, or intolerance to aminoglycosides * had any clinically significant or chronic medical condition or any major surgery within the past 5 years which * have any surgery planned during the study * had any chronic use of any systemic medications, including immunosuppressant's, oral corticosteroids or other immune-modifying drugs, within the 12 months prior to screening * received any vaccination within the 28 days prior to screening * received any prescription medicines (except hormonal contraception for wocbp) within 14 days prior to visit 0 (screening) or over the counter medicines (except paracetamol and acetaminophen at a dose of (≤2 grams/day)) within 48 hours of visit 0. * have a known history or a positive test of hiv 1 or 2, hep b, or hep c * have a positive rtpcr test for sars-cov-2 within 2 days of screening * documented history of previous infection with sars-cov-2 and/or who have the presence of serum ab indicative of a previous sars-cov-2 infection * have a history of hypersensitivity or have had a serious reaction to a previous vaccination * have any abnormality or permanent body art (eg, tattoo) that, would obstruct the ability to observe local reactions at the injection site. * have a condition known to put them at high risk for severe covid-19, including those with any of the following risk factors: hypertension, diabetes mellitus, chronic pulmonary disease, asthma, chronic liver disease, known stage 3 or worse chronic kidney disease * anticipating the need for immunosuppressive treatment within the next 6 months. other inclusion or exclusion criteria may apply.

- have had any acute illness with or without fever, within 72 hours prior to the first vaccination - symptoms of upper respiratory infection, fever, persistent cough, shortness of breath, runny nose and breathing difficulties - breastfeeding or who plan to breastfeed during the study - have a known allergy, hypersensitivity, or intolerance to aminoglycosides - had any clinically significant or chronic medical condition or any major surgery within the past 5 years which - have any surgery planned during the study - had any chronic use of any systemic medications, including immunosuppressant's, oral corticosteroids or other immune-modifying drugs, within the 12 months prior to screening - received any vaccination within the 28 days prior to screening - received any prescription medicines (except hormonal contraception for wocbp) within 14 days prior to visit 0 (screening) or over the counter medicines (except paracetamol and acetaminophen at a dose of (≤2 grams/day)) within 48 hours of visit 0. - have a known history or a positive test of hiv 1 or 2, hep b, or hep c - have a positive rtpcr test for sars-cov-2 within 2 days of screening - documented history of previous infection with sars-cov-2 and/or who have the presence of serum ab indicative of a previous sars-cov-2 infection - have a history of hypersensitivity or have had a serious reaction to a previous vaccination - have any abnormality or permanent body art (eg, tattoo) that, would obstruct the ability to observe local reactions at the injection site. - have a condition known to put them at high risk for severe covid-19, including those with any of the following risk factors: hypertension, diabetes mellitus, chronic pulmonary disease, asthma, chronic liver disease, known stage 3 or worse chronic kidney disease - anticipating the need for immunosuppressive treatment within the next 6 months. other inclusion or exclusion criteria may apply.

- have had any acute illness with or without fever, within 72 hours prior to the first vaccination - symptoms of upper respiratory infection, fever, persistent cough, shortness of breath, runny nose and breathing difficulties - breastfeeding or who plan to breastfeed during the study - have a known allergy, hypersensitivity, or intolerance to aminoglycosides - had any clinically significant or chronic medical condition or any major surgery within the past 5 years which - have any surgery planned during the study - had any chronic use of any systemic medications, including immunosuppressant's, oral corticosteroids or other immune-modifying drugs, within the 12 months prior to screening - received any vaccination within the 28 days prior to screening - received any prescription medicines (except hormonal contraception for wocbp) within 14 days prior to visit 0 (screening) or over the counter medicines (except paracetamol and acetaminophen at a dose of (≤2 grams/day)) within 48 hours of visit 0. - have a known history or a positive test of hiv 1 or 2, hep b, or hep c - have a positive rtpcr test for sars-cov-2 within 2 days of screening - documented history of previous infection with sars-cov-2 and/or who have the presence of serum ab indicative of a previous sars-cov-2 infection - have a history of hypersensitivity or have had a serious reaction to a previous vaccination - have any abnormality or permanent body art (eg, tattoo) that, would obstruct the ability to observe local reactions at the injection site. - have a condition known to put them at high risk for severe covid-19, including those with any of the following risk factors: hypertension, diabetes mellitus, chronic pulmonary disease, asthma, chronic liver disease, known stage 3 or worse chronic kidney disease - anticipating the need for immunosuppressive treatment within the next 6 months. other inclusion or exclusion criteria may apply.