* patients who have received treatment with any form of ozone therapy 6 months before admission to the hospital. * patients who have previously been treated and have experienced some type of adverse reaction to ozone therapy. * patients aware of having a deficiency of glucose-6-phosphate dehydrogenase. * patients with clinically decompensated chronic comorbidities, independently of covid-19. * patients suffering from any psychiatric disorder specified in axis i of the diagnostic and statistical manual of mental disorders (dsm-v), other than major depression. * patients who are not able to clearly understand the objectives and methodology of the study. * pregnant or lactating patients.

* patients who have received treatment with any form of ozone therapy 6 months before admission to the hospital. * patients who have previously been treated and have experienced some type of adverse reaction to ozone therapy. * patients aware of having a deficiency of glucose-6-phosphate dehydrogenase. * patients with clinically decompensated chronic comorbidities, independently of covid-19. * patients suffering from any psychiatric disorder specified in axis i of the diagnostic and statistical manual of mental disorders (dsm-v), other than major depression. * patients who are not able to clearly understand the objectives and methodology of the study. * pregnant or lactating patients.

- patients who have received treatment with any form of ozone therapy 6 months before admission to the hospital. - patients who have previously been treated and have experienced some type of adverse reaction to ozone therapy. - patients aware of having a deficiency of glucose-6-phosphate dehydrogenase. - patients with clinically decompensated chronic comorbidities, independently of covid-19. - patients suffering from any psychiatric disorder specified in axis i of the diagnostic and statistical manual of mental disorders (dsm-v), other than major depression. - patients who are not able to clearly understand the objectives and methodology of the study. - pregnant or lactating patients.

- patients who have received treatment with any form of ozone therapy 6 months before admission to the hospital. - patients who have previously been treated and have experienced some type of adverse reaction to ozone therapy. - patients aware of having a deficiency of glucose-6-phosphate dehydrogenase. - patients with clinically decompensated chronic comorbidities, independently of covid-19. - patients suffering from any psychiatric disorder specified in axis i of the diagnostic and statistical manual of mental disorders (dsm-v), other than major depression. - patients who are not able to clearly understand the objectives and methodology of the study. - pregnant or lactating patients.