inclusion criteria: * healthy adults, or stable medical condition for adults with pre-existing medical conditions. a stable medical condition is defined as disease not requiring significant change in therapy or hospitalization for worsening disease during 3 months before enrolment, nor expected to require any significant change in therapy or hospitalization for worsening disease in foreseeable future. * understands and agrees to comply with the study procedures (visits, phone calls) and provides written free informed consent. * able to comply with study procedures based on investigator judgement. * affiliated to a social security system, (except state medical aid)

inclusion criteria: * healthy adults, or stable medical condition for adults with pre-existing medical conditions. a stable medical condition is defined as disease not requiring significant change in therapy or hospitalization for worsening disease during 3 months before enrolment, nor expected to require any significant change in therapy or hospitalization for worsening disease in foreseeable future. * understands and agrees to comply with the study procedures (visits, phone calls) and provides written free informed consent. * able to comply with study procedures based on investigator judgement. * affiliated to a social security system, (except state medical aid)

inclusion criteria: - healthy adults, or stable medical condition for adults with pre-existing medical conditions. a stable medical condition is defined as disease not requiring significant change in therapy or hospitalization for worsening disease during 3 months before enrolment, nor expected to require any significant change in therapy or hospitalization for worsening disease in foreseeable future. - understands and agrees to comply with the study procedures (visits, phone calls) and provides written free informed consent. - able to comply with study procedures based on investigator judgement. - affiliated to a social security system, (except state medical aid)

inclusion criteria: - healthy adults, or stable medical condition for adults with pre-existing medical conditions. a stable medical condition is defined as disease not requiring significant change in therapy or hospitalization for worsening disease during 3 months before enrolment, nor expected to require any significant change in therapy or hospitalization for worsening disease in foreseeable future. - understands and agrees to comply with the study procedures (visits, phone calls) and provides written free informed consent. - able to comply with study procedures based on investigator judgement. - affiliated to a social security system, (except state medical aid)