1. on home/therapy oxygen (i.e. for copd patients) at baseline prior to development of covid-19 2. is already enrolled in a clinical trial using immunotherapeutic regimen for covid-19 3. already gammacore for other medical conditions 4. a history of aneurysm, intracranial hemorrhage, brain tumors, or significant head trauma 5. known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (eg, bruits or history of transient ischemic attack or cerebrovascular accident), congestive heart failure, known severe coronary artery disease, or recent myocardial infarction 6. uncontrolled high blood pressure (\>140/90) 7. current implantation of an electrical and/or neurostimulator device, including but not limited to a cardiac pacemaker or defibrillator, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant 8. current implantation of metal cervical spine hardware or a metallic implant near the gammacore stimulation site 9. belongs to a vulnerable population or has any condition such that his or her ability to provide informed consent, comply with the follow-up requirements, or provide self-assessments is compromised (e.g. homeless, developmentally disabled and prisoner) 10. compromised access to peripheral veinous for blood) 11. pregnant women

1. on home/therapy oxygen (i.e. for copd patients) at baseline prior to development of covid-19 2. is already enrolled in a clinical trial using immunotherapeutic regimen for covid-19 3. already gammacore for other medical conditions 4. a history of aneurysm, intracranial hemorrhage, brain tumors, or significant head trauma 5. known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (eg, bruits or history of transient ischemic attack or cerebrovascular accident), congestive heart failure, known severe coronary artery disease, or recent myocardial infarction 6. uncontrolled high blood pressure (\>140/90) 7. current implantation of an electrical and/or neurostimulator device, including but not limited to a cardiac pacemaker or defibrillator, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant 8. current implantation of metal cervical spine hardware or a metallic implant near the gammacore stimulation site 9. belongs to a vulnerable population or has any condition such that his or her ability to provide informed consent, comply with the follow-up requirements, or provide self-assessments is compromised (e.g. homeless, developmentally disabled and prisoner) 10. compromised access to peripheral veinous for blood) 11. pregnant women

on home/therapy oxygen (i.e. for copd patients) at baseline prior to development of covid-19 is already enrolled in a clinical trial using immunotherapeutic regimen for covid-19 already gammacore for other medical conditions a history of aneurysm, intracranial hemorrhage, brain tumors, or significant head trauma known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (eg, bruits or history of transient ischemic attack or cerebrovascular accident), congestive heart failure, known severe coronary artery disease, or recent myocardial infarction uncontrolled high blood pressure (>140/90) current implantation of an electrical and/or neurostimulator device, including but not limited to a cardiac pacemaker or defibrillator, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant current implantation of metal cervical spine hardware or a metallic implant near the gammacore stimulation site belongs to a vulnerable population or has any condition such that his or her ability to provide informed consent, comply with the follow-up requirements, or provide self-assessments is compromised (e.g. homeless, developmentally disabled and prisoner) compromised access to peripheral veinous for blood) pregnant women

on home/therapy oxygen (i.e. for copd patients) at baseline prior to development of covid-19 is already enrolled in a clinical trial using immunotherapeutic regimen for covid-19 already gammacore for other medical conditions a history of aneurysm, intracranial hemorrhage, brain tumors, or significant head trauma known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (eg, bruits or history of transient ischemic attack or cerebrovascular accident), congestive heart failure, known severe coronary artery disease, or recent myocardial infarction uncontrolled high blood pressure (>140/90) current implantation of an electrical and/or neurostimulator device, including but not limited to a cardiac pacemaker or defibrillator, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant current implantation of metal cervical spine hardware or a metallic implant near the gammacore stimulation site belongs to a vulnerable population or has any condition such that his or her ability to provide informed consent, comply with the follow-up requirements, or provide self-assessments is compromised (e.g. homeless, developmentally disabled and prisoner) compromised access to peripheral veinous for blood) pregnant women

1. on home/therapy oxygen (i.e. for copd patients) at baseline prior to development of covid-19 2. is already enrolled in a clinical trial using immunotherapeutic regimen for covid-19 3. already gammacore for other medical conditions 4. a history of aneurysm, intracranial hemorrhage, brain tumors, or significant head trauma 5. known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (eg, bruits or history of transient ischemic attack or cerebrovascular accident), congestive heart failure, known severe coronary artery disease, or recent myocardial infarction 6. uncontrolled high blood pressure (>140/90) 7. current implantation of an electrical and/or neurostimulator device, including but not limited to a cardiac pacemaker or defibrillator, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant 8. current implantation of metal cervical spine hardware or a metallic implant near the gammacore stimulation site 9. belongs to a vulnerable population or has any condition such that his or her ability to provide informed consent, comply with the follow-up requirements, or provide self-assessments is compromised (e.g. homeless, developmentally disabled and prisoner) 10. compromised access to peripheral veinous for blood) 11. pregnant women

1. on home/therapy oxygen (i.e. for copd patients) at baseline prior to development of covid-19 2. is already enrolled in a clinical trial using immunotherapeutic regimen for covid-19 3. already gammacore for other medical conditions 4. a history of aneurysm, intracranial hemorrhage, brain tumors, or significant head trauma 5. known or suspected severe atherosclerotic cardiovascular disease, severe carotid artery disease (eg, bruits or history of transient ischemic attack or cerebrovascular accident), congestive heart failure, known severe coronary artery disease, or recent myocardial infarction 6. uncontrolled high blood pressure (>140/90) 7. current implantation of an electrical and/or neurostimulator device, including but not limited to a cardiac pacemaker or defibrillator, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant 8. current implantation of metal cervical spine hardware or a metallic implant near the gammacore stimulation site 9. belongs to a vulnerable population or has any condition such that his or her ability to provide informed consent, comply with the follow-up requirements, or provide self-assessments is compromised (e.g. homeless, developmentally disabled and prisoner) 10. compromised access to peripheral veinous for blood) 11. pregnant women