inclusion criteria: * individuals aged 18 to 65 years old at the time of consent. * residing within the area of the study and planning to stay for the study duration. * hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). * female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception\* recommended by the national health system up to 12 weeks after the booster vaccination.. * agreement to refrain from blood donation during the course of the study. * able and willing to comply with all study requirements, based on the assessment of the investigator. * willingness to provide written informed consent before any trial procedure \* effective contraception is defined as follows: contraceptive medications delivered orally, intramuscularly, vaginally, or implanted underneath the skin, surgical methods (hysterectomy or bilateral tubal ligation), condoms, diaphragms, intrauterine device (iud), and abstinence.

inclusion criteria: * individuals aged 18 to 65 years old at the time of consent. * residing within the area of the study and planning to stay for the study duration. * hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). * female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception\* recommended by the national health system up to 12 weeks after the booster vaccination.. * agreement to refrain from blood donation during the course of the study. * able and willing to comply with all study requirements, based on the assessment of the investigator. * willingness to provide written informed consent before any trial procedure \* effective contraception is defined as follows: contraceptive medications delivered orally, intramuscularly, vaginally, or implanted underneath the skin, surgical methods (hysterectomy or bilateral tubal ligation), condoms, diaphragms, intrauterine device (iud), and abstinence.

inclusion criteria: individuals aged 18 to 65 years old at the time of consent. residing within the area of the study and planning to stay for the study duration. hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception* recommended by the national health system up to 12 weeks after the booster vaccination.. agreement to refrain from blood donation during the course of the study. able and willing to comply with all study requirements, based on the assessment of the investigator. willingness to provide written informed consent before any trial procedure * effective contraception is defined as follows: contraceptive medications delivered orally, intramuscularly, vaginally, or implanted underneath the skin, surgical methods (hysterectomy or bilateral tubal ligation), condoms, diaphragms, intrauterine device (iud), and abstinence.

inclusion criteria: individuals aged 18 to 65 years old at the time of consent. residing within the area of the study and planning to stay for the study duration. hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception* recommended by the national health system up to 12 weeks after the booster vaccination.. agreement to refrain from blood donation during the course of the study. able and willing to comply with all study requirements, based on the assessment of the investigator. willingness to provide written informed consent before any trial procedure * effective contraception is defined as follows: contraceptive medications delivered orally, intramuscularly, vaginally, or implanted underneath the skin, surgical methods (hysterectomy or bilateral tubal ligation), condoms, diaphragms, intrauterine device (iud), and abstinence.

inclusion criteria: individuals aged 18 to 65 years old at the time of consent. residing within the maputo health region and planning to stay for the study duration. hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception* recommended by the national health system up to 12 weeks after the booster vaccination.. agreement to refrain from blood donation during the course of the study. able and willing to comply with all study requirements, based on the assessment of the investigator. willingness to provide written informed consent before any trial procedure * effective contraception is defined as follows: contraceptive medications delivered orally, intramuscularly, vaginally, or implanted underneath the skin, surgical methods (hysterectomy or bilateral tubal ligation), condoms, diaphragms, intrauterine device (iud), and abstinence.

inclusion criteria: individuals aged 18 to 65 years old at the time of consent. residing within the maputo health region and planning to stay for the study duration. hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception* recommended by the national health system up to 12 weeks after the booster vaccination.. agreement to refrain from blood donation during the course of the study. able and willing to comply with all study requirements, based on the assessment of the investigator. willingness to provide written informed consent before any trial procedure * effective contraception is defined as follows: contraceptive medications delivered orally, intramuscularly, vaginally, or implanted underneath the skin, surgical methods (hysterectomy or bilateral tubal ligation), condoms, diaphragms, intrauterine device (iud), and abstinence.

inclusion criteria: - healthy female and male adults 18 to 65 years old at the time of consent. - residing within the maputo health region and planning to stay for the study duration. - hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). - female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception recommended by the national health system up to 12 weeks after the booster vaccination. - agreement to refrain from blood donation during the course of the study. - able and willing to comply with all study requirements, , based on the assessment of the investigator. - willingness to provide written informed consent before any trial procedure

inclusion criteria: - healthy female and male adults 18 to 65 years old at the time of consent. - residing within the maputo health region and planning to stay for the study duration. - hiv negative test result on the day of screening (for those who do not have a documented hiv test results in the last three months of screening). - female volunteers of childbearing potential with a negative pregnancy test on the day(s) of screening and vaccination, practicing/willing to practice continuous effective contraception recommended by the national health system up to 12 weeks after the booster vaccination. - agreement to refrain from blood donation during the course of the study. - able and willing to comply with all study requirements, , based on the assessment of the investigator. - willingness to provide written informed consent before any trial procedure