inclusion criteria: 1. availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; 2. boys and girls aged 12-17 inclusive; 3. negative test result for hiv, hepatitis, syphilis; 4. a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; 5. a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; 6. no history of covid-2019; 7. absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); 8. consent to the use of effective contraceptive methods during the entire period of participation in the study; 9. negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); 10. negative test for the presence of drugs and psychostimulants in the urine at the screening visit; 11. negative alcohol test at screening visit; 12. no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; 13. absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: 1. availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; 2. boys and girls aged 12-17 inclusive; 3. negative test result for hiv, hepatitis, syphilis; 4. a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; 5. a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; 6. no history of covid-2019; 7. absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); 8. consent to the use of effective contraceptive methods during the entire period of participation in the study; 9. negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); 10. negative test for the presence of drugs and psychostimulants in the urine at the screening visit; 11. negative alcohol test at screening visit; 12. no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; 13. absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; boys and girls aged 12-17 inclusive; negative test result for hiv, hepatitis, syphilis; a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; no history of covid-2019; absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); consent to the use of effective contraceptive methods during the entire period of participation in the study; negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); negative test for the presence of drugs and psychostimulants in the urine at the screening visit; negative alcohol test at screening visit; no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; boys and girls aged 12-17 inclusive; negative test result for hiv, hepatitis, syphilis; a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; no history of covid-2019; absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); consent to the use of effective contraceptive methods during the entire period of participation in the study; negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); negative test for the presence of drugs and psychostimulants in the urine at the screening visit; negative alcohol test at screening visit; no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: 1. availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; 2. boys and girls aged 12-17 inclusive; 3. negative test result for hiv, hepatitis, syphilis; 4. a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; 5. a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; 6. no history of covid-2019; 7. absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); 8. consent to the use of effective contraceptive methods during the entire period of participation in the study; 9. negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); 10. negative test for the presence of drugs and psychostimulants in the urine at the screening visit; 11. negative alcohol test at screening visit; 12. no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; 13. absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: 1. availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; 2. boys and girls aged 12-17 inclusive; 3. negative test result for hiv, hepatitis, syphilis; 4. a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; 5. a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; 6. no history of covid-2019; 7. absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); 8. consent to the use of effective contraceptive methods during the entire period of participation in the study; 9. negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); 10. negative test for the presence of drugs and psychostimulants in the urine at the screening visit; 11. negative alcohol test at screening visit; 12. no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; 13. absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; boys and girls aged 12-17 inclusive; negative test result for hiv, hepatitis, syphilis; a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; no history of covid-2019; absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); consent to the use of effective contraceptive methods during the entire period of participation in the study; negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); negative test for the presence of drugs and psychostimulants in the urine at the screening visit; negative alcohol test at screening visit; no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; boys and girls aged 12-17 inclusive; negative test result for hiv, hepatitis, syphilis; a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; no history of covid-2019; absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); consent to the use of effective contraceptive methods during the entire period of participation in the study; negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); negative test for the presence of drugs and psychostimulants in the urine at the screening visit; negative alcohol test at screening visit; no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: 1. availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; 2. boys and girls aged 12-17 inclusive; 3. negative test result for hiv, hepatitis, syphilis; 4. a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; 5. a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; 6. no history of covid-2019; 7. absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); 8. consent to the use of effective contraceptive methods during the entire period of participation in the study; 9. negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); 10. negative test for the presence of drugs and psychostimulants in the urine at the screening visit; 11. negative alcohol test at screening visit; 12. no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; 13. absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study

inclusion criteria: 1. availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; 2. boys and girls aged 12-17 inclusive; 3. negative test result for hiv, hepatitis, syphilis; 4. a negative test result for the presence of igm and igg antibodies to sars cov2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the moscow city health department 7 days prior to inclusion in the study can be taken into account; 5. a negative test result for covid-2019, determined by the pcr method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the moscow city health department 7 days before being included in the study; 6. no history of covid-2019; 7. absence of contact of the research subject with covid-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); 8. consent to the use of effective contraceptive methods during the entire period of participation in the study; 9. negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); 10. negative test for the presence of drugs and psychostimulants in the urine at the screening visit; 11. negative alcohol test at screening visit; 12. no history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; 13. absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study