1. alt or ast \>5 times the upper limit of normal 2. history of blood clots 3. history of breast cancer 4. allergy to progesterone or betacyclodextrin 5. use of supplemental oxygen prior to hospital admission 6. requiring higher than 50% supplemental oxygen by high flow nasal cannula or mechanical ventilation

1. alt or ast \>5 times the upper limit of normal 2. history of blood clots 3. history of breast cancer 4. allergy to progesterone or betacyclodextrin 5. use of supplemental oxygen prior to hospital admission 6. requiring higher than 50% supplemental oxygen by high flow nasal cannula or mechanical ventilation

alt or ast >5 times the upper limit of normal history of blood clots history of breast cancer allergy to progesterone or betacyclodextrin use of supplemental oxygen prior to hospital admission requiring higher than 50% supplemental oxygen by high flow nasal cannula or mechanical ventilation

alt or ast >5 times the upper limit of normal history of blood clots history of breast cancer allergy to progesterone or betacyclodextrin use of supplemental oxygen prior to hospital admission requiring higher than 50% supplemental oxygen by high flow nasal cannula or mechanical ventilation

1. alt or ast >5 times the upper limit of normal 2. history of blood clots 3. history of breast cancer 4. allergy to progesterone or betacyclodextrin 5. use of supplemental oxygen prior to hospital admission 6. requiring higher than 50% supplemental oxygen by high flow nasal cannula or mechanical ventilation

1. alt or ast >5 times the upper limit of normal 2. history of blood clots 3. history of breast cancer 4. allergy to progesterone or betacyclodextrin 5. use of supplemental oxygen prior to hospital admission 6. requiring higher than 50% supplemental oxygen by high flow nasal cannula or mechanical ventilation