inclusion criteria: 1. hospitalized adult male and female patients, including women of childbearing potential, at least 18 years of age, inclusive. women of childbearing potential must agree to the protocol-specific contraception requirements. 2. participant (or legally authorized representative) capable of giving signed informed consent. 3. laboratory-confirmed novel coronavirus (sars-cov-2) infection. 4. evidence of pneumonia assessed by all of the following: 1. radiographic imaging (eg, chest x-ray, chest computed tomography \[ct\] scan, etc.); and 2. clinical assessment (evidence of rales/crackles on exam); and 3. spo2 ≤94% on room air. 5. evidence of increased inflammation as assessed by hscrp \> uln and at least one of the following being \> uln (as available): 1. ferritin; 2. procalcitonin; 3. d-dimer; 4. fibrinogen; 5. ldh; 6. pt/ptt.

inclusion criteria: 1. hospitalized adult male and female patients, including women of childbearing potential, at least 18 years of age, inclusive. women of childbearing potential must agree to the protocol-specific contraception requirements. 2. participant (or legally authorized representative) capable of giving signed informed consent. 3. laboratory-confirmed novel coronavirus (sars-cov-2) infection. 4. evidence of pneumonia assessed by all of the following: 1. radiographic imaging (eg, chest x-ray, chest computed tomography \[ct\] scan, etc.); and 2. clinical assessment (evidence of rales/crackles on exam); and 3. spo2 ≤94% on room air. 5. evidence of increased inflammation as assessed by hscrp \> uln and at least one of the following being \> uln (as available): 1. ferritin; 2. procalcitonin; 3. d-dimer; 4. fibrinogen; 5. ldh; 6. pt/ptt.

inclusion criteria: hospitalized adult male and female patients, including women of childbearing potential, at least 18 years of age, inclusive. women of childbearing potential must agree to the protocol-specific contraception requirements. participant (or legally authorized representative) capable of giving signed informed consent. laboratory-confirmed novel coronavirus (sars-cov-2) infection. evidence of pneumonia assessed by all of the following: radiographic imaging (eg, chest x-ray, chest computed tomography [ct] scan, etc.); and clinical assessment (evidence of rales/crackles on exam); and spo2 ≤94% on room air. evidence of increased inflammation as assessed by hscrp > uln and at least one of the following being > uln (as available): ferritin; procalcitonin; d-dimer; fibrinogen; ldh; pt/ptt.

inclusion criteria: hospitalized adult male and female patients, including women of childbearing potential, at least 18 years of age, inclusive. women of childbearing potential must agree to the protocol-specific contraception requirements. participant (or legally authorized representative) capable of giving signed informed consent. laboratory-confirmed novel coronavirus (sars-cov-2) infection. evidence of pneumonia assessed by all of the following: radiographic imaging (eg, chest x-ray, chest computed tomography [ct] scan, etc.); and clinical assessment (evidence of rales/crackles on exam); and spo2 ≤94% on room air. evidence of increased inflammation as assessed by hscrp > uln and at least one of the following being > uln (as available): ferritin; procalcitonin; d-dimer; fibrinogen; ldh; pt/ptt.

inclusion criteria: 1. hospitalized adult male and female patients, including women of childbearing potential, at least 18 years of age, inclusive. women of childbearing potential must agree to the protocol-specific contraception requirements. 2. participant (or legally authorized representative) capable of giving signed informed consent. 3. laboratory-confirmed novel coronavirus (sars-cov-2) infection. 4. evidence of pneumonia assessed by all of the following: 1. radiographic imaging (eg, chest x-ray, chest computed tomography [ct] scan, etc.); and 2. clinical assessment (evidence of rales/crackles on exam); and 3. spo2 ≤94% on room air. 5. evidence of increased inflammation as assessed by hscrp > uln and at least one of the following being > uln (as available): 1. ferritin; 2. procalcitonin; 3. d-dimer; 4. fibrinogen; 5. ldh; 6. pt/ptt.

inclusion criteria: 1. hospitalized adult male and female patients, including women of childbearing potential, at least 18 years of age, inclusive. women of childbearing potential must agree to the protocol-specific contraception requirements. 2. participant (or legally authorized representative) capable of giving signed informed consent. 3. laboratory-confirmed novel coronavirus (sars-cov-2) infection. 4. evidence of pneumonia assessed by all of the following: 1. radiographic imaging (eg, chest x-ray, chest computed tomography [ct] scan, etc.); and 2. clinical assessment (evidence of rales/crackles on exam); and 3. spo2 ≤94% on room air. 5. evidence of increased inflammation as assessed by hscrp > uln and at least one of the following being > uln (as available): 1. ferritin; 2. procalcitonin; 3. d-dimer; 4. fibrinogen; 5. ldh; 6. pt/ptt.