* patients with red flag indicators as chest pain, critical drop of oxygen saturation which require oxygen supply, severe level of hypoxia (blue lips) * unconscious patient * positive covid-19 patients * patients with cognitive impairment * end-stage of chronic diseases * bmi more than 30 kg/m2 * history of other cardiovascular disease as coronary artery disease, valvular heart disease, cardiac arrhythmias, congestive heart failure, myocardial infarction, stroke, transient ischemic attack, or peripheral vascular disease * neurological, neuromuscular, and musculoskeletal limitations * current active infection * developmental disability or cognitive impairment that in the opinion of the investigator would preclude adequate comprehension of the informed consent form and/or ability to record the necessary study measurements. * participation in a clinical study or other type of research in the past 30 days

* patients with red flag indicators as chest pain, critical drop of oxygen saturation which require oxygen supply, severe level of hypoxia (blue lips) * unconscious patient * positive covid-19 patients * patients with cognitive impairment * end-stage of chronic diseases * bmi more than 30 kg/m2 * history of other cardiovascular disease as coronary artery disease, valvular heart disease, cardiac arrhythmias, congestive heart failure, myocardial infarction, stroke, transient ischemic attack, or peripheral vascular disease * neurological, neuromuscular, and musculoskeletal limitations * current active infection * developmental disability or cognitive impairment that in the opinion of the investigator would preclude adequate comprehension of the informed consent form and/or ability to record the necessary study measurements. * participation in a clinical study or other type of research in the past 30 days

- patients with red flag indicators as chest pain, critical drop of oxygen saturation which require oxygen supply, severe level of hypoxia (blue lips) - unconscious patient - positive covid-19 patients - patients with cognitive impairment - end-stage of chronic diseases - bmi more than 30 kg/m2 - history of other cardiovascular disease as coronary artery disease, valvular heart disease, cardiac arrhythmias, congestive heart failure, myocardial infarction, stroke, transient ischemic attack, or peripheral vascular disease - neurological, neuromuscular, and musculoskeletal limitations - current active infection - developmental disability or cognitive impairment that in the opinion of the investigator would preclude adequate comprehension of the informed consent form and/or ability to record the necessary study measurements. - participation in a clinical study or other type of research in the past 30 days

- patients with red flag indicators as chest pain, critical drop of oxygen saturation which require oxygen supply, severe level of hypoxia (blue lips) - unconscious patient - positive covid-19 patients - patients with cognitive impairment - end-stage of chronic diseases - bmi more than 30 kg/m2 - history of other cardiovascular disease as coronary artery disease, valvular heart disease, cardiac arrhythmias, congestive heart failure, myocardial infarction, stroke, transient ischemic attack, or peripheral vascular disease - neurological, neuromuscular, and musculoskeletal limitations - current active infection - developmental disability or cognitive impairment that in the opinion of the investigator would preclude adequate comprehension of the informed consent form and/or ability to record the necessary study measurements. - participation in a clinical study or other type of research in the past 30 days