inclusion criteria: 1. ability to provide written informed consent (by the parents or legally acceptable/authorized representative (lar) and assent by the children (verbal/oral assent for the children of age between 7-12 years, and written assent for the children of age between \>12 to 18 years), and audio video consent for all participants. 2. participants of either gender of age between ≥2 to ≤18years (participant should be ≤18 years at the time of screening of the study). 3. good general health as determined by the discretion of investigator. 4. expressed interest and availability to fulfill the study requirements. 5. agrees not to participate in another clinical trial at any time during the study period. 6. agrees to remain in the study area for the entire duration of the study. 7. willing to allow storage and future use of biological samples for future research.

inclusion criteria: 1. ability to provide written informed consent (by the parents or legally acceptable/authorized representative (lar) and assent by the children (verbal/oral assent for the children of age between 7-12 years, and written assent for the children of age between \>12 to 18 years), and audio video consent for all participants. 2. participants of either gender of age between ≥2 to ≤18years (participant should be ≤18 years at the time of screening of the study). 3. good general health as determined by the discretion of investigator. 4. expressed interest and availability to fulfill the study requirements. 5. agrees not to participate in another clinical trial at any time during the study period. 6. agrees to remain in the study area for the entire duration of the study. 7. willing to allow storage and future use of biological samples for future research.

inclusion criteria: ability to provide written informed consent (by the parents or legally acceptable/authorized representative (lar) and assent by the children (verbal/oral assent for the children of age between 7-12 years, and written assent for the children of age between >12 to 18 years), and audio video consent for all participants. participants of either gender of age between ≥2 to ≤18years (participant should be ≤18 years at the time of screening of the study). good general health as determined by the discretion of investigator. expressed interest and availability to fulfill the study requirements. agrees not to participate in another clinical trial at any time during the study period. agrees to remain in the study area for the entire duration of the study. willing to allow storage and future use of biological samples for future research.

inclusion criteria: ability to provide written informed consent (by the parents or legally acceptable/authorized representative (lar) and assent by the children (verbal/oral assent for the children of age between 7-12 years, and written assent for the children of age between >12 to 18 years), and audio video consent for all participants. participants of either gender of age between ≥2 to ≤18years (participant should be ≤18 years at the time of screening of the study). good general health as determined by the discretion of investigator. expressed interest and availability to fulfill the study requirements. agrees not to participate in another clinical trial at any time during the study period. agrees to remain in the study area for the entire duration of the study. willing to allow storage and future use of biological samples for future research.

inclusion criteria: 1. ability to provide written informed consent (by the parents or legally acceptable/authorized representative (lar) and assent by the children (verbal/oral assent for the children of age between 7-12 years, and written assent for the children of age between >12 to 18 years), and audio video consent for all participants. 2. participants of either gender of age between ≥2 to ≤18years (participant should be ≤18 years at the time of screening of the study). 3. good general health as determined by the discretion of investigator. 4. expressed interest and availability to fulfill the study requirements. 5. agrees not to participate in another clinical trial at any time during the study period. 6. agrees to remain in the study area for the entire duration of the study. 7. willing to allow storage and future use of biological samples for future research.

inclusion criteria: 1. ability to provide written informed consent (by the parents or legally acceptable/authorized representative (lar) and assent by the children (verbal/oral assent for the children of age between 7-12 years, and written assent for the children of age between >12 to 18 years), and audio video consent for all participants. 2. participants of either gender of age between ≥2 to ≤18years (participant should be ≤18 years at the time of screening of the study). 3. good general health as determined by the discretion of investigator. 4. expressed interest and availability to fulfill the study requirements. 5. agrees not to participate in another clinical trial at any time during the study period. 6. agrees to remain in the study area for the entire duration of the study. 7. willing to allow storage and future use of biological samples for future research.