* any significant acute or chronic medical condition that in the opinion of the vaccinator makes the participant unsuitable for participation in the study or jeopardises the safety of the participant. * participant reports being pregnant. * history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine. test negative vaccine effectiveness case-control study the study population consists of individuals presenting at the participating hospitals and health centres during the study period, who: either * are hospitalized (or died) for an illness consistent with possible covid-19. or (in case of other hospital controls) * presented to the emergency department (ed) for reasons other than a covid-19 like illness (e.g. trauma or elective surgery). and * meet the inclusion criteria. inclusion criteria: * ever eligible to receive az1222 vaccine following the national immunization recommendations prior to hospital admission. and * willing and able to provide informed consent.

* any significant acute or chronic medical condition that in the opinion of the vaccinator makes the participant unsuitable for participation in the study or jeopardises the safety of the participant. * participant reports being pregnant. * history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine. test negative vaccine effectiveness case-control study the study population consists of individuals presenting at the participating hospitals and health centres during the study period, who: either * are hospitalized (or died) for an illness consistent with possible covid-19. or (in case of other hospital controls) * presented to the emergency department (ed) for reasons other than a covid-19 like illness (e.g. trauma or elective surgery). and * meet the inclusion criteria. inclusion criteria: * ever eligible to receive az1222 vaccine following the national immunization recommendations prior to hospital admission. and * willing and able to provide informed consent.

- any significant acute or chronic medical condition that in the opinion of the vaccinator makes the participant unsuitable for participation in the study or jeopardises the safety of the participant. - participant reports being pregnant. - history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine. test negative vaccine effectiveness case-control study the study population consists of individuals presenting at the participating hospitals and health centres during the study period, who: either - are hospitalized (or died) for an illness consistent with possible covid-19. or (in case of other hospital controls) - presented to the emergency department (ed) for reasons other than a covid-19 like illness (e.g. trauma or elective surgery). and - meet the inclusion criteria. inclusion criteria: - ever eligible to receive az1222 vaccine following the national immunization recommendations prior to hospital admission. and - willing and able to provide informed consent.

- any significant acute or chronic medical condition that in the opinion of the vaccinator makes the participant unsuitable for participation in the study or jeopardises the safety of the participant. - participant reports being pregnant. - history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine. test negative vaccine effectiveness case-control study the study population consists of individuals presenting at the participating hospitals and health centres during the study period, who: either - are hospitalized (or died) for an illness consistent with possible covid-19. or (in case of other hospital controls) - presented to the emergency department (ed) for reasons other than a covid-19 like illness (e.g. trauma or elective surgery). and - meet the inclusion criteria. inclusion criteria: - ever eligible to receive az1222 vaccine following the national immunization recommendations prior to hospital admission. and - willing and able to provide informed consent.