inclusion criteria: * laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen (can be documented from inpatient medical record) * hospitalized with at least "severe" covid-19-induced ard or ards as defined per fda guidance; covid-19: developing drugs and biological products for treatment or prevention * requires oxygen supplementation at screening * willing to follow contraception guidelines

inclusion criteria: * laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen (can be documented from inpatient medical record) * hospitalized with at least "severe" covid-19-induced ard or ards as defined per fda guidance; covid-19: developing drugs and biological products for treatment or prevention * requires oxygen supplementation at screening * willing to follow contraception guidelines

inclusion criteria: - laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen (can be documented from inpatient medical record) - hospitalized with at least "severe" covid-19-induced ard or ards as defined per fda guidance; covid-19: developing drugs and biological products for treatment or prevention - requires oxygen supplementation at screening - willing to follow contraception guidelines

inclusion criteria: - laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen (can be documented from inpatient medical record) - hospitalized with at least "severe" covid-19-induced ard or ards as defined per fda guidance; covid-19: developing drugs and biological products for treatment or prevention - requires oxygen supplementation at screening - willing to follow contraception guidelines

inclusion criteria: - laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen - hospitalized with covid-19-induced ard or ards as defined per fda guidance; covid-19: developing drugs and biological products for treatment or prevention - requires oxygen supplementation at screening - willing to follow contraception guidelines

inclusion criteria: - laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen - hospitalized with covid-19-induced ard or ards as defined per fda guidance; covid-19: developing drugs and biological products for treatment or prevention - requires oxygen supplementation at screening - willing to follow contraception guidelines

inclusion criteria: - laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen - hospitalized with covid-19-induced ard or ards (any severity) with a pao2/fio2 (pf ratio) ≤ 300 - requires oxygen supplementation at screening - willing to follow contraception guidelines

inclusion criteria: - laboratory-confirmed sars-cov-2 infection as determined by an approved polymerase chain reaction (pcr) or an approved antigen test of any specimen - hospitalized with covid-19-induced ard or ards (any severity) with a pao2/fio2 (pf ratio) ≤ 300 - requires oxygen supplementation at screening - willing to follow contraception guidelines