inclusion criteria: 1. male or non-pregnant female \> 18 years of age at the time of consent 2. confirmedsars-cov-2 infection 3. disease severity necessitating hospitalization 4. currently taking supplemental oxygen 5. no anticipated need (within 24 hours) for mechanical ventilation, defined as: 1. positive clinical response to oxygen supplementation with improvement in hypoxia or 2. hypoxia improvement with bronchospasm therapy if bronchospasm present exclusion criteria 1. egfr \< 50 2. known glucose-6-phosphate dehydrogenase (g6pd) deficiency 3. anticipated need for mechanical ventilation within 24 hours 4. pregnant or breastfeeding 5. requires home oxygen for any reason

inclusion criteria: 1. male or non-pregnant female \> 18 years of age at the time of consent 2. confirmedsars-cov-2 infection 3. disease severity necessitating hospitalization 4. currently taking supplemental oxygen 5. no anticipated need (within 24 hours) for mechanical ventilation, defined as: 1. positive clinical response to oxygen supplementation with improvement in hypoxia or 2. hypoxia improvement with bronchospasm therapy if bronchospasm present exclusion criteria 1. egfr \< 50 2. known glucose-6-phosphate dehydrogenase (g6pd) deficiency 3. anticipated need for mechanical ventilation within 24 hours 4. pregnant or breastfeeding 5. requires home oxygen for any reason

inclusion criteria: male or non-pregnant female > 18 years of age at the time of consent confirmedsars-cov-2 infection disease severity necessitating hospitalization currently taking supplemental oxygen no anticipated need (within 24 hours) for mechanical ventilation, defined as: positive clinical response to oxygen supplementation with improvement in hypoxia or hypoxia improvement with bronchospasm therapy if bronchospasm present exclusion criteria egfr < 50 known glucose-6-phosphate dehydrogenase (g6pd) deficiency anticipated need for mechanical ventilation within 24 hours pregnant or breastfeeding requires home oxygen for any reason

inclusion criteria: male or non-pregnant female > 18 years of age at the time of consent confirmedsars-cov-2 infection disease severity necessitating hospitalization currently taking supplemental oxygen no anticipated need (within 24 hours) for mechanical ventilation, defined as: positive clinical response to oxygen supplementation with improvement in hypoxia or hypoxia improvement with bronchospasm therapy if bronchospasm present exclusion criteria egfr < 50 known glucose-6-phosphate dehydrogenase (g6pd) deficiency anticipated need for mechanical ventilation within 24 hours pregnant or breastfeeding requires home oxygen for any reason

inclusion criteria: 1. male or non-pregnant female > 18 years of age at the time of consent 2. confirmedsars-cov-2 infection 3. disease severity necessitating hospitalization 4. currently taking supplemental oxygen 5. no anticipated need (within 24 hours) for mechanical ventilation, defined as: 1. positive clinical response to oxygen supplementation with improvement in hypoxia or 2. hypoxia improvement with bronchospasm therapy if bronchospasm present exclusion criteria 1. egfr < 50 2. known glucose-6-phosphate dehydrogenase (g6pd) deficiency 3. anticipated need for mechanical ventilation within 24 hours 4. pregnant or breastfeeding 5. requires home oxygen for any reason

inclusion criteria: 1. male or non-pregnant female > 18 years of age at the time of consent 2. confirmedsars-cov-2 infection 3. disease severity necessitating hospitalization 4. currently taking supplemental oxygen 5. no anticipated need (within 24 hours) for mechanical ventilation, defined as: 1. positive clinical response to oxygen supplementation with improvement in hypoxia or 2. hypoxia improvement with bronchospasm therapy if bronchospasm present exclusion criteria 1. egfr < 50 2. known glucose-6-phosphate dehydrogenase (g6pd) deficiency 3. anticipated need for mechanical ventilation within 24 hours 4. pregnant or breastfeeding 5. requires home oxygen for any reason