inclusion criteria: 1. above 18 years of age 2. have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs 3. classified as severe\* covid-19 according to who guideline (5l-15l of oxygen requirement on fm, nrm) 4. consent given by the patient or first degree relative

inclusion criteria: 1. above 18 years of age 2. have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs 3. classified as severe\* covid-19 according to who guideline (5l-15l of oxygen requirement on fm, nrm) 4. consent given by the patient or first degree relative

inclusion criteria: above 18 years of age have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs classified as severe* covid-19 according to who guideline (5l-15l of oxygen requirement on fm, nrm) consent given by the patient or first degree relative

inclusion criteria: above 18 years of age have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs classified as severe* covid-19 according to who guideline (5l-15l of oxygen requirement on fm, nrm) consent given by the patient or first degree relative

inclusion criteria: above 18 years of age have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs classified as severe* covid-19 according to who guideline consent given by the patient or first degree relative

inclusion criteria: above 18 years of age have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs classified as severe* covid-19 according to who guideline consent given by the patient or first degree relative

inclusion criteria: 1. above 18 years of age 2. have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs 3. classified as severe* covid-19 according to who guideline 4. consent given by the patient or first degree relative

inclusion criteria: 1. above 18 years of age 2. have positive covid pcr on nasopharyngeal and/or oropharyngeal swabs 3. classified as severe* covid-19 according to who guideline 4. consent given by the patient or first degree relative