* history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) * serious chronic disorder that in the investigator's opinion would make the participant inappropriate for entry into the study * previous clinical or microbiological diagnosis of covid-19 * previous vaccination with any investigational pneumococcal vaccine, or planned receipt of any licensed or investigational pneumococcal vaccine through study participation * previous vaccination with any coronavirus vaccine, other than those received in study c4591001 * other medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study

* history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) * serious chronic disorder that in the investigator's opinion would make the participant inappropriate for entry into the study * previous clinical or microbiological diagnosis of covid-19 * previous vaccination with any investigational pneumococcal vaccine, or planned receipt of any licensed or investigational pneumococcal vaccine through study participation * previous vaccination with any coronavirus vaccine, other than those received in study c4591001 * other medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study

- history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) - serious chronic disorder that in the investigator's opinion would make the participant inappropriate for entry into the study - previous clinical or microbiological diagnosis of covid-19 - previous vaccination with any investigational pneumococcal vaccine, or planned receipt of any licensed or investigational pneumococcal vaccine through study participation - previous vaccination with any coronavirus vaccine, other than those received in study c4591001 - other medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study

- history of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) - serious chronic disorder that in the investigator's opinion would make the participant inappropriate for entry into the study - previous clinical or microbiological diagnosis of covid-19 - previous vaccination with any investigational pneumococcal vaccine, or planned receipt of any licensed or investigational pneumococcal vaccine through study participation - previous vaccination with any coronavirus vaccine, other than those received in study c4591001 - other medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study