inclusion criteria: * age ≥18 years old * confirmed covid-19 positive by pcr * within 24 hours of mechanical ventilation (eti arm) or within 24 hours of needing either cpap or niv (cpap/niv arm) * assent or professional assent obtained

inclusion criteria: * age ≥18 years old * confirmed covid-19 positive by pcr * within 24 hours of mechanical ventilation (eti arm) or within 24 hours of needing either cpap or niv (cpap/niv arm) * assent or professional assent obtained

inclusion criteria: age ≥18 years old confirmed covid-19 positive by pcr within 24 hours of mechanical ventilation (eti arm) or within 24 hours of needing either cpap or niv (cpap/niv arm) assent or professional assent obtained

inclusion criteria: age ≥18 years old confirmed covid-19 positive by pcr within 24 hours of mechanical ventilation (eti arm) or within 24 hours of needing either cpap or niv (cpap/niv arm) assent or professional assent obtained

inclusion criteria: - age ≥18 years old - confirmed covid-19 positive by pcr - within 24 hours of mechanical ventilation - assent or professional assent obtained

inclusion criteria: - age ≥18 years old - confirmed covid-19 positive by pcr - within 24 hours of mechanical ventilation - assent or professional assent obtained