1. active tumor disease. 2. pregnancy. 3. participation in another active clinical trial. 4. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. 5. not consent to participation.

1. active tumor disease. 2. pregnancy. 3. participation in another active clinical trial. 4. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. 5. not consent to participation.

active tumor disease. pregnancy. participation in another active clinical trial. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. not consent to participation.

active tumor disease. pregnancy. participation in another active clinical trial. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. not consent to participation.

active tumor disease. pregnancy. participation in another clinical trial for the same pathology. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. lack of signed consent for participation.

active tumor disease. pregnancy. participation in another clinical trial for the same pathology. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. lack of signed consent for participation.

1. active tumor disease. 2. pregnancy. 3. participation in another clinical trial for the same pathology. 4. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. 5. lack of signed consent for participation.

1. active tumor disease. 2. pregnancy. 3. participation in another clinical trial for the same pathology. 4. any circumstance that in the researcher's opinion justifies the patient's non-participation in the trial. 5. lack of signed consent for participation.