1. known severe allergic reaction to remdesivir or to other antiviral drugs 2. patients already having other treatments like tocilizumab or other antiviral drugs 3. pregnancy or breastfeeding 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) \>5 times upper normal limit 5. creatinine clearance \<30ml/min 6. low platelet count \<50,000/l

1. known severe allergic reaction to remdesivir or to other antiviral drugs 2. patients already having other treatments like tocilizumab or other antiviral drugs 3. pregnancy or breastfeeding 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) \>5 times upper normal limit 5. creatinine clearance \<30ml/min 6. low platelet count \<50,000/l

known severe allergic reaction to remdesivir or to other antiviral drugs patients already having other treatments like tocilizumab or other antiviral drugs pregnancy or breastfeeding alanine aminotransferase (alt) or aspartate aminotransferase (ast) >5 times upper normal limit creatinine clearance <30ml/min low platelet count <50,000/l

known severe allergic reaction to remdesivir or to other antiviral drugs patients already having other treatments like tocilizumab or other antiviral drugs pregnancy or breastfeeding alanine aminotransferase (alt) or aspartate aminotransferase (ast) >5 times upper normal limit creatinine clearance <30ml/min low platelet count <50,000/l

1. known severe allergic reaction to remdesivir or to other antiviral drugs 2. patients already having other treatments like tocilizumab or other antiviral drugs 3. pregnancy or breastfeeding 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) >5 times upper normal limit 5. creatinine clearance <30ml/min 6. low platelet count <50,000/l

1. known severe allergic reaction to remdesivir or to other antiviral drugs 2. patients already having other treatments like tocilizumab or other antiviral drugs 3. pregnancy or breastfeeding 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) >5 times upper normal limit 5. creatinine clearance <30ml/min 6. low platelet count <50,000/l