1. participation in any other clinical trial of an experimental treatment for covid-19. 2. evidence of multiorgan failure. 3. mechanically ventilated for \> 5 days. 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) \> 5 x upper limit of normal (uln). 5. creatinine clearance \< 50 ml/min.

1. participation in any other clinical trial of an experimental treatment for covid-19. 2. evidence of multiorgan failure. 3. mechanically ventilated for \> 5 days. 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) \> 5 x upper limit of normal (uln). 5. creatinine clearance \< 50 ml/min.

participation in any other clinical trial of an experimental treatment for covid-19. evidence of multiorgan failure. mechanically ventilated for > 5 days. alanine aminotransferase (alt) or aspartate aminotransferase (ast) > 5 x upper limit of normal (uln). creatinine clearance < 50 ml/min.

participation in any other clinical trial of an experimental treatment for covid-19. evidence of multiorgan failure. mechanically ventilated for > 5 days. alanine aminotransferase (alt) or aspartate aminotransferase (ast) > 5 x upper limit of normal (uln). creatinine clearance < 50 ml/min.

1. participation in any other clinical trial of an experimental treatment for covid-19. 2. evidence of multiorgan failure. 3. mechanically ventilated for > 5 days. 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) > 5 x upper limit of normal (uln). 5. creatinine clearance < 50 ml/min.

1. participation in any other clinical trial of an experimental treatment for covid-19. 2. evidence of multiorgan failure. 3. mechanically ventilated for > 5 days. 4. alanine aminotransferase (alt) or aspartate aminotransferase (ast) > 5 x upper limit of normal (uln). 5. creatinine clearance < 50 ml/min.