inclusion criteria: * age of ≥18 years * laboratory-confirmed sars-cov-2 infection during the current admission * on invasive, non-invasive mechanical ventilation (niv) (peep ≥5 cmh20) or high-flow nasal canula (hfnc) oxygen therapy (minimum total flow rate of 40 lpm) * ards (onset \<96h) as per the international consensus definition (p/f ratio \< 300 with peep ≥5cm h20 or on hfnc), not due primarily to cardiac causes.

inclusion criteria: * age of ≥18 years * laboratory-confirmed sars-cov-2 infection during the current admission * on invasive, non-invasive mechanical ventilation (niv) (peep ≥5 cmh20) or high-flow nasal canula (hfnc) oxygen therapy (minimum total flow rate of 40 lpm) * ards (onset \<96h) as per the international consensus definition (p/f ratio \< 300 with peep ≥5cm h20 or on hfnc), not due primarily to cardiac causes.

inclusion criteria: - age of ≥18 years - laboratory-confirmed sars-cov-2 infection during the current admission - on invasive, non-invasive mechanical ventilation (niv) (peep ≥5 cmh20) or high-flow nasal canula (hfnc) oxygen therapy (minimum total flow rate of 40 lpm) - ards (onset <96h) as per the international consensus definition (p/f ratio < 300 with peep ≥5cm h20 or on hfnc), not due primarily to cardiac causes.

inclusion criteria: - age of ≥18 years - laboratory-confirmed sars-cov-2 infection during the current admission - on invasive, non-invasive mechanical ventilation (niv) (peep ≥5 cmh20) or high-flow nasal canula (hfnc) oxygen therapy (minimum total flow rate of 40 lpm) - ards (onset <96h) as per the international consensus definition (p/f ratio < 300 with peep ≥5cm h20 or on hfnc), not due primarily to cardiac causes.